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Understanding Migraine-Related Brain Fog and Memory Loss

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Understanding Migraine-Related Brain Fog and Memory Loss

People with migraine often report problems with memory loss, but the link remains unclear. Factors relating to both migraine and brain fog, such as pain, fatigue, and difficulty focusing, may help explain patterns of memory loss with migraine, although experts are still unsure.

Elizabeth Seng, PhD, a psychology and neurology professor at Yeshiva University in New York City, who will speak about cognitive issues during the 2025 Migraine World Summit, says people are more likely to report memory loss interictally (between migraine episodes), but it’s not clear why.

Memory Loss or Something Else?

“It is … common to misattribute attention issues to memory loss,” Begasse de Dhaem says. “If someone isn’t able to pay attention or concentrate during or around a migraine attack and then doesn’t recall the information they learned, it’s not that they forgot or experienced memory loss; it’s that they had difficulty paying attention.”

Cogniphobia

During her Migraine World Summit interview, Dr. Seng also proposes cogniphobia as a possible cause of difficulty thinking, especially between attacks.

Cogniphobia is when a person is afraid to think or reason too much in case it triggers an attack. This fear of thinking “too hard” between attacks may result in losing the habit of thinking hard over time. What appears to be long-term cognitive decline may in fact be an avoidance strategy.

In a study published in 2022, people who met the criteria for cogniphobia found it hard to remember images in the short and longer term, suggesting a link between cogniphobia and memory loss.

The links between migraine and cognitive impairment are complex. However, the relationship between migraine and memory loss may become clearer as scientists learn more about migraine and its underlying mechanisms.

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