Many people with psoriasis also experience varying levels of psychological distress from the condition.
While social factors like self-esteem issues or embarrassment over how psoriasis physically looks can worsen mental health issues, research suggests other factors can contribute to depression as well.
Inflammation
As in the case with many autoimmune diseases, one of the primary causes of psoriasis is inflammation. With psoriasis, the lack of regulation within the immune system that leads to inflammation can also play a role in the development of depression.
“This is one reason why individuals with psoriasis and other inflammatory conditions may have higher rates of depression and anxiety,” Khan says.
Physical Discomfort
Reduced Self-Esteem and Isolation
A skin condition like psoriasis can lead to social withdrawal, Khan says. This is particularly true when affected areas are highly visible.
Hannah Kopelman, DO, a dermatologist with Kopelman Aesthetic Surgery and Kopelman Hair Restoration in New York City, says this is often the case with psoriasis, which commonly affects the scalp, elbows, arms, and knees.
Some with psoriasis feel concern about how the public or loved ones will react to their skin’s appearance. “One of the most common things with psoriasis is that people don’t want to leave their house because they’re depressed by their skin manifestations,” Dr. Kopelman says.
This impact on self-esteem can lead to social avoidance. “The social withdrawal, avoidance of intimate relationships, and anxiety about public perception can lead to feelings of loneliness, which is a significant risk factor for depression,” Khan says.
“Low self-esteem is common in individuals with psoriasis, particularly if they have experienced bullying, comments about their appearance, or rejection due to their condition,” he says.
Co-occurring Conditions
Because psoriatic arthritis has the potential to affect mobility, this can further contribute to social isolation and make someone less likely to engage in things that them bring joy, Kopelman says.
Navigating additional health concerns alongside a visible skin condition can prove overwhelming. This can ultimately lead to worsening depression.
