Postpartum depression may result from a combination of different factors. Researchers believe that, in general, genetics, hormonal changes, and emotional issues are key contributors.
“After giving birth, hormone concentrations drop by a hundredfold within a matter of days,” says Katherine Wisner, MD, the director of the Asher Center for the Study and Treatment of Depressive Disorders at Northwestern Medicine in Chicago. The sudden plunge may create disturbances in mood, particularly in women who have a prior history of depression or anxiety.
Periods of hormonal fluctuation, such as menstrual cycles or perimenopause, are associated with major depressive episodes, adds Dr. Wisner. The fluctuations that occur during and after pregnancy may affect certain neurotransmitters (chemical messengers in the brain) or brain function in other ways.
“This massive drop in hormones, along with the initiation of breastfeeding, disrupted sleep, and adapting to motherhood, all contribute to the risk of developing depression,” Wisner says.
Risk Factors for Postpartum Depression
- History of depression or bipolar disorder
- Symptoms of depression during or after a previous pregnancy
- Having family member who’s been diagnosed with depression, postpartum depression, or another mood disorder like premenstrual dysphoric disorder
- Having a stressful life event within the past year, such as job loss, death of a loved one, domestic violence, or personal illness
- Medical complications during childbirth, such as premature delivery or having a baby with medical problems
- Having twins, triplets, or other multiple births
- Having conflict or relationship issues with your spouse or partner
- Having an unwanted or unplanned pregnancy
- Having mixed feelings about the pregnancy
- A lack of strong emotional support from others
- Having financial difficulties
- Being younger than 20
- Being a single parent
- Having a baby with medical needs
- Having a baby who cries very often