Women Under 50 Are More Likely to Be Diagnosed With Cancer Than Men

Women under 65 — especially younger adults — are more likely than men in the same age group to be diagnosed with cancer, according to a new report from the American Cancer Society.

The report did highlight some good news: Cancer mortality rates in the United States have dropped 34 percent over the past 30 years, driven in large part by fewer deaths from the four most common malignancies: breast, colorectal, lung, and prostate cancers, according to findings published in CA: A Cancer Journal for Clinicians.

Despite these survival gains, the report also highlights some concerning trends for American women.

Among adults under 50 years old, women are about 82 percent more likely than men in that age group to get a cancer diagnosis, up from 51 percent higher odds roughly two decades ago, according to the report.

Middle-aged women, meanwhile, are now slightly more likely to get cancer than men, who for most of the past two decades had surpassed women in diagnosis rates, the report also found.

“Continued reductions in cancer mortality because of drops in smoking, better treatment, and earlier detection is certainly great news,” says the lead study author, Rebecca Siegel, MPH, the senior scientific director of surveillance research at the American Cancer Society.

“However, this progress is tempered by rising incidence in young and middle-aged women, who are often the family caregivers, and a shifting cancer burden from men to women,” Siegel says.

Why Are More Younger Women Getting Cancer Than Men?

Several factors are combining to make women under 50 in particular more vulnerable to cancer than men, Dr. Siegel says.

Obesity, for example, accounts for roughly twice as many cancer cases in women as in men, Siegel says.

Women today are also having fewer children and at later ages, two factors that are contributing to an increase in breast and uterine cancers, Siegel adds.

Binge drinking, which increases the risk of breast and several other types of cancers, is also becoming more common among women in their thirties and forties, Siegel notes.

“Things like obesity, physical inactivity, diets low in fiber and high in processed food, and alcohol intake have increased over the past decades overall, and in younger people, and we’re seeing their consequences younger, too,” says Erica Warner, ScD, MPH, an assistant professor at Harvard Medical School and Massachusetts General Hospital in Boston who wasn’t involved in the new report.

Women of Color Have Higher Cancer Risks

Racial disparities persist in both cancer diagnoses and death rates that may make certain women particularly susceptible to developing or dying of cancer, the report suggests.

Overall, people who identify as American Indian or Alaskan Native (AIAN) had the highest overall cancer incidence and mortality rates among women, the report found. AIAN people also had the highest death rates from cervical cancer, colorectal tumors, and lung cancer.

Black women, however, had the highest mortality rates from breast cancer, according to the report. Black women were also two to three times more likely to die of uterine or endometrial cancers than any other racial group.

How Women Can Reduce Their Cancer Risk

Because many of the factors driving the increased cancer risk for women are related to lifestyle, there are steps people can take to minimize their odds of developing or dying of cancer, Dr. Warner says.

“I always tell people that there are some risks for cancer that are beyond our control, like genetics,” Warner says. “But we can try to control what we can, to the best of our abilities, through lifestyle.”

Good preventive habits, Warners says, include:

  • A diet rich in fruits and vegetables that limits processed foods and alcohol
  • As much physical activity as possible
  • Enough sleep
  • Stress management
  • Positive social connections with friends and family

Staying up-to-date on mammograms and other recommended cancer screenings is also key for women to minimize their risk, Warner adds.

“These are all things that can help us have healthier minds and bodies, reduce the risk of cancer, and if you do develop cancer, find it when it is most treatable or potentially curable,” Warner says.

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MMR Vaccine for Measles, Mumps, and Rubella: What You Need to Know

The MMR vaccine is a powerful tool to prevent three highly contagious viral diseases: measles, mumps, and rubella (German measles). Thanks to the MMR vaccine, introduced in 1963, these serious illnesses are much less common today than they once were.
Overview What It Is What Is the MMR Vaccine? The MMR vaccine is an injection, usually given in the upper arm. Two doses (shots) are needed for full protection. It is a live attenuated vaccine, meaning it contains living but weakened viruses that are not strong enough to cause disease. They teach the immune system to recognize and fight the actual viruses if the body is exposed to them in the future.
Why Get the MMR Vaccine? Why Get It The MMR vaccine protects against a trio of illnesses that can cause severe and in some cases life-threatening complications. Measles is one of the world’s most contagious diseases. If one person has it, up to 9 out of 10 people nearby will catch it unless they are vaccinated.e60dc2a1-f33c-4a05-9b50-8e3e8e5976294bb48e63-4fe6-492e-b0f2-d0e48b4e8c93 Possible complications include pneumonia, encephalitis (brain swelling), and even death.e60dc2a1-f33c-4a05-9b50-8e3e8e5976294bb48e63-4fe6-492e-b0f2-d0e48b4e8c93 From 2000 to 2023, measles vaccination saved an estimated 60 million lives worldwide.e60dc2a1-f33c-4a05-9b50-8e3e8e5976294271c46d-31f5-4cb9-a89d-c81f51dae715 Mumps, known for painful swelling of the salivary glands, can result in hearing loss and infertility. Rubella, also called German measles, is generally mild in children but can lead to birth defects in babies if a pregnant person gets sick. Vaccination not only protects you, it also protects vulnerable people around you.e60dc2a1-f33c-4a05-9b50-8e3e8e59762977a3ca89-a798-44a2-852d-6b56ed1bc36d
Who Should Get the MMR Vaccine? Who Should Get It The MMR vaccine is recommended for everyone who hasn’t been vaccinated or had these diseases. This includes:e60dc2a1-f33c-4a05-9b50-8e3e8e5976295fcd0f52-6ade-44f8-8f33-75da9105159d Children: All children need two doses of the MMR vaccine, with the first dose given at 12 to 15 months of age, and the second dose at 4 to 6 years old. Students at post-high school educational institutions: Those who don’t have presumptive evidence of immunity (see definition below) need 2 doses of MMR vaccine, separated by at least 28 days. Adults: People who don’t have presumptive evidence of immunity should get at least 1 dose of the MMR vaccine. Some individuals should get two doses, separated by at least 28 days, if they are entering a situation where they face a heightened risk of measles or mumps transmission. This includes students at post-high school educational institutions; healthcare personnel; and international travelers. International travelers: The CDC recommends the following vaccination schedule. Infants Babies ages 6 through 11 months should get one dose of MMR vaccine. Infants who get one dose of MMR vaccine before their first birthday should get two more doses (one at 12 through 15 months of age and another separated by at least 28 days). Children It’s advised that children 12 months of age and older receive two doses of MMR vaccine, separated by at least 28 days. Teenagers and Adults Those who do not have presumptive evidence of immunity against measles should get two doses of MMR vaccine separated by at least 28 days. Healthcare personnel: Healthcare workers who don’t have presumptive evidence of immunity should get two MMR vaccine doses, separated by at least 28 days. Women of childbearing age: Women should check with their healthcare provider to make sure they have presumptive evidence of immunity before getting pregnant. Women of childbearing age who do not have presumptive evidence of immunity and are not pregnant should get at least 1 dose of the MMR vaccine. Groups at increased risk of mumps during a mumps outbreak: During a mumps outbreak certain groups of individuals at increased risk of mumps transmission (perhaps because they may be living in close quarters with someone who has mumps, for instance) may need an extra MMR vaccine dose. What Is Presumptive Evidence of Immunity? Presumptive evidence of immunity can be established in any of the following ways:e60dc2a1-f33c-4a05-9b50-8e3e8e597629b3aa34c1-7a64-40f8-905b-44e362a9c639 Written documentation of having had the vaccines Lab evidence of immunity Lab confirmation of the disease Birth year before 1957
Who Shouldn’t Get the MMR Vaccine? Who Shouldn’t Get It Some health conditions or other risk factors make a live virus vaccine like MMR unsafe.e60dc2a1-f33c-4a05-9b50-8e3e8e597629172e8f7e-e0fe-4f77-99df-e963c44bf709 Pregnancy The MMR vaccine is not advised during pregnancy. If you plan to get pregnant, talk to your provider about getting the MMR vaccine before you conceive. Immunosuppression People who have a weakened immune system or are otherwise immunocompromised should not get the MMR vaccine. Family History of Immune Issues Anyone with a parent or sibling with a history of immune system issues is not a candidate for this vaccine. Certain Health Conditions The MMR vaccine is not safe for people with a history of any condition that causes bleeding or bruising. Recent Blood Transfusion People who have received any recent blood product should avoid the MMR vaccine, usually for at least three months. Tuberculosis Severe Allergic Reactions People who have had an allergic reaction to any component of the MMR vaccine, including gelatin or neomycin, should not receive it. Recent Vaccinations People who received any other vaccination in the past month should wait to get the MMR vaccine. If you’re unsure whether the MMR vaccine is right for you or your child, talk to your healthcare provider.
Types of MMR Vaccine Vaccine Types Two MMR vaccines are available for use in the United States, M-M-R II and PRIORIX. They are fully interchangeable. The MMRV vaccine protects against varicella (chicken pox) as well as measles, mumps, and rubella. It is an option for children 12 months through 12 years of age.e60dc2a1-f33c-4a05-9b50-8e3e8e5976295c8be8ec-ab64-403f-8e50-ef9607112249
How Well Does the MMR Vaccine Work? Effectiveness Full immunization with two doses the MMR vaccine is 97 percent effective at preventing measles and rubella and 88 percent effective at preventing mumps. Inadequate levels of vaccination at the community and national level can threaten so-called herd immunity. For measles, preventing outbreaks requires that at least 95 percent of the population get both vaccine doses. There were an estimated 10 million cases of measles worldwide in 2023, a 20 percent increase from 2022, due to inadequate immunization coverage. Globally, only 3 in 4 children received the recommended second dose of the MMR vaccine needed for full protection.e60dc2a1-f33c-4a05-9b50-8e3e8e597629e3708f29-1fc4-42e6-bdc8-d90ed551da86
How Long Does the MMR Vaccine Last? How Long It Lasts People who receive both doses of the MMR vaccine according to the recommended vaccination schedule are usually considered protected for life against measles and rubella.e60dc2a1-f33c-4a05-9b50-8e3e8e5976292452bc76-b042-4a6d-9718-dfb4d75ea839 Immunity against mumps may decrease over time, however, and some people may no longer be protected against mumps later in life. These individuals should talk to a healthcare provider about getting an additional vaccine dose in the event of a mumps outbreak. Do Adults Need a Booster Shot? In general, adults who have had two doses of the MMR vaccine as children do not need a booster shot. It’s very rare to get measles if you’re fully vaccinated. If you are vaccinated and get the measles, it’s more likely to be a mild case. But if you’re unsure about your vaccination history or immunity status, ask your healthcare provider whether you need a booster shot. There aren’t significant risks to receiving an extra dose.e60dc2a1-f33c-4a05-9b50-8e3e8e597629aecfe4ab-5448-4c51-b067-ac3f8b171c73 In the event of a mumps outbreak, you may need an additional dose of the MMR shot.e60dc2a1-f33c-4a05-9b50-8e3e8e5976292452bc76-b042-4a6d-9718-dfb4d75ea839
Side Effects of the MMR Vaccine Side Effects Like all vaccines, the MMR vaccine can cause side effects , but they are usually mild and short-lived. Possible side effects include: Arm pain from getting the shot Fever Mild rash Temporary joint pain and stiffness (mostly in teenage or adult women) More rarely, people may experience swelling in the cheeks or neck. These side effects typically go away within a few days.
Is the MMR Vaccine Safe? Safety Serious complications from the MMR vaccine are extremely rare. These include: Immune Thrombocytopenic Purpura (ITP) The MMR vaccine can cause a temporary low platelet count, which can cause immune thrombocytopenic purpura (ITP). This bleeding disorder usually goes away without treatment in children, but can become chronic in some adults. Febrile Seizures Studies have shown that there is a small increased risk of febrile seizures (convulsions caused by a fever) in children under 7 years old about 8 to 14 days after vaccination. This happens in about 1 out of every 3,000 to 4,000 children.e60dc2a1-f33c-4a05-9b50-8e3e8e597629cee61947-4309-423b-ab99-ab5aa7d136ed A child should be seen by a doctor as soon as possible after a febrile seizure. If the child also has a stiff neck, is vomiting, has breathing problems, or is extremely sleepy, call 911.e60dc2a1-f33c-4a05-9b50-8e3e8e5976290cae2a09-9980-4876-b5ef-13faf7c88daa Measles Inclusion Body Encephalitis In extremely uncommon cases almost always involving people with weakened immune systems, someone who contracts the wild-type measles virus may develop this kind of severe brain swelling. There have been three published reports of vaccinated people developing this condition, with one traced to the measles vaccine strain itself.e60dc2a1-f33c-4a05-9b50-8e3e8e597629cee61947-4309-423b-ab99-ab5aa7d136ed Anaphylaxis People may experience a severe allergic reaction (anaphylaxis) in response to a component in the vaccine. If you experience any serious changes after vaccination, like trouble breathing or swelling of the throat, seek medical attention immediately. If you have concerns about vaccine side effects or allergies, discuss them with your healthcare provider.e60dc2a1-f33c-4a05-9b50-8e3e8e597629cee61947-4309-423b-ab99-ab5aa7d136ed
Does the MMR Vaccine Cause Autism? Autism Fears The claim that the MMR vaccine causes autism is based on flawed, discredited research and has been thoroughly debunked by multiple studies. The controversy began with a 1998 study by the English scientist Andrew Wakefield, published in the medical journal the Lancet, which suggested a link between the MMR vaccine and autism. But the Lancet later retracted the study due to serious scientific misconduct on Wakefield’s part, including misrepresentation of data.e60dc2a1-f33c-4a05-9b50-8e3e8e59762999367056-6de4-4fcb-9ee9-1034ca20adcc Dozens of recent and well-designed studies have refuted this connection.e60dc2a1-f33c-4a05-9b50-8e3e8e597629ee836b43-3d2d-4a8a-91b8-c72610d6c7dd One of the largest which included over 500,000 children found that the risk of autism was the same in both vaccinated and unvaccinated children.e60dc2a1-f33c-4a05-9b50-8e3e8e597629cdfb94fe-f388-489d-b9b6-4dbeea4ba89c
Can the MMR Vaccine Give You the Measles? The MMR vaccine cannot give you measles. The vaccine contains weakened forms of the living viruses, but they are not strong enough to cause disease.e60dc2a1-f33c-4a05-9b50-8e3e8e597629457fbc6e-d13e-49fa-95cf-56b196dbc526
MMR Vaccine Cost and Insurance Coverage Cost Most insurance plans, including Medicaid, cover the full cost of the vaccine. All health insurance marketplace plans cover certain vaccines, including the MMR vaccine.e60dc2a1-f33c-4a05-9b50-8e3e8e5976296de727c2-2650-484e-aefb-d8bdba98d794 If you don’t have insurance, you may also be able to get the vaccine for free at local health clinics or through programs that provide vaccines to uninsured or underinsured individuals. Eligible children who aren’t covered by health insurance can get no-cost vaccines at the CDC program Vaccines for Children (VFC).e60dc2a1-f33c-4a05-9b50-8e3e8e59762937ec5667-e305-4da3-87c5-2dfa66c2153a If you don’t have insurance or qualify for assistance, the cost of the MMR vaccine will vary depending on where you receive it.
Where to Get an MMR Vaccine Near You You can get the MMR vaccine at many healthcare providers’ offices, pharmacies, and local health departments. Visit Vaccines.gov to find a location near you.e60dc2a1-f33c-4a05-9b50-8e3e8e5976291c6f5bca-7048-48b7-9494-3358ab6fac5e
The Takeaway The MMR vaccine protects against measles, mumps, and rubella, all of which can cause severe illness. The vaccine is recommended for nearly everyone, with a two-dose schedule for children and certain adults. Large-scale studies have proven that the MMR vaccine does not cause autism. Serious complications from vaccination are rare.
Resources We Trust Mayo Clinic: Measles, Mumps, and Rubella Virus Vaccine Live (Subcutaneous Route, Intramuscular Route)Centers for Disease Control and Prevention: Measles, Mumps, and Rubella (MMR) Vaccination: What Everyone Should KnowCleveland Clinic: MMR VaccineYale Medicine: MeaslesChildren’s Hospital of Philadelphia: Vaccines and Autism

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Bronchitis vs. Pneumonia: What’s the Difference?

Bronchitis vs. Pneumonia: What Are the Differences and Similarities?

Acute bronchitis is a condition in which the lining of your bronchial tubes becomes inflamed. These are the passages that carry air to and from your lungs. This condition usually develops as a result of a viral infection like a cold or the flu, and it typically gets better in about one to two weeks.

It is different than chronic bronchitis, which is a condition that does not go away and is marked by a recurring cough and other symptoms that can be managed but not cured.

 Chronic bronchitis is less likely to be mistaken for pneumonia than acute bronchitis.
Pneumonia is an infection in one or both lungs. The cause can be bacterial, viral, or fungal. When you have pneumonia, the air sacs of the lungs (alveoli) fill up with fluid or pus.

 While anyone can get pneumonia, some people — such as children, the elderly, people with asthma, and individuals with chronic diseases — have an increased risk of developing it.

Your risk of getting pneumonia is higher if you spend a lot of time in a crowded environment such as military barracks or nursing homes, or around infected animals. Cigarette smoking and using drugs or alcohol also put you at higher risk. Conditions that weaken your immune system may also increase your pneumonia risk, as can lung diseases such as asthma, cystic fibrosis, or COPD.

Both bronchitis and pneumonia involve inflammation in the chest. The key difference is that the inflammation occurs in different parts of the chest.

 That said, both conditions share some common symptoms:

  • Cough (often accompanied by the production of mucus)
  • Fatigue
  • Shortness of breath that can get worse when you’re active
  • Fever and chills

Bronchitis can also cause chest discomfort and wheezing.

Pneumonia, meanwhile, can bring on these symptoms not usually linked to bronchitis:

  • Excessive sweating and clammy skin
  • Sharp pain in the chest, especially when breathing deeply or coughing
  • Headache
  • Loss of appetite
  • Lack of energy
  • Confusion
  • Nausea, diarrhea, and vomiting

While the symptoms of bronchitis or pneumonia can range from mild to serious enough to require hospitalization, symptoms such as fever, breathing problems, and chest pain tend to be more severe with pneumonia.

In people with pneumonia, the alveoli fill with pus and other fluids and prevent oxygen from reaching the bloodstream. When there’s too little oxygen in the blood, the body cannot function properly, increasing the risk of death.

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Normal, Dry, Oily, Sensitive, or Combination

If You Have Normal Skin …

Normal skin tends to be balanced — neither oily nor dry. At its healthiest, normal skin is smooth, radiant, and hydrated, with no inflammation, says Baumann.

To care for normal skin, start with the basics:

  • Wash twice daily with a gentle cleanser
  • Apply broad-spectrum SPF 30 sunscreen in the morning
  • Moisturize at night

Those with normal skin can apply just about any product or ingredient without developing issues, Hartman says.

That may not be all you need, depending on your life stage or skin concern like discolorations or fine lines and wrinkles. You might choose additional products to brighten or stimulate the production of collagen (a type of protein) to address lines.

If You Have Dry Skin …

Skin becomes dry when it loses water faster than it gets replaced. This causes skin to appear dull and feel tight, flaky, and rough, Hartman says. If the skin loses too much moisture, it may crack, itch, burn, or sting.

  • Environment Deodorant soaps and harsh cleaning products strip moisturizing oils and fats from the skin. Cold, dry climates or a job that requires frequent handwashing or harsh chemicals (such as nursing, cooking, and housekeeping) also makes the skin prone to dryness.
  • Medications Dry skin is a potential side effect of certain medications, such as statins and diuretics.
  • Health Conditions Diabetes, thyroid disease, and kidney disease can cause excessively dry skin. In addition, dry skin is a common symptom of skin conditions such as atopic dermatitis (eczema), psoriasis, ichthyosis, and seborrheic dermatitis (scalp eczema).
  • Nutrient Deficiencies Skin needs vitamins and minerals to stay healthy. If you don’t get the vitamin D, vitamin A, niacin, zinc, or iron your skin needs, it can become dry.
  • Age As we get older, our skin makes less sebum (an oil that hydrates and softens skin), with a dramatic drop by the age of 40. Skin that produces less oil is more prone to dryness.
  • Skin Color People with brown, black, or fair skin are more likely to have dry skin that those with a medium complexion.

In general, dry skin is best suited to cleansers and moisturizers that include ceramides, the building blocks of the skin barrier, Hartman says. When choosing moisturizers and sunscreens, look for thicker formulas like oils, ointments, and creams.

If over-the-counter (OTC) moisturizers don’t do the trick, see a dermatologist. They may prescribe a moisturizer with stronger active ingredients.

Hartman advises that dry skin types avoid alcohol-based products because they can worsen dryness and lead to irritation, bumps, and redness.

To help your skin heal and prevent it from drying out even more, wash with a gentle, fragrance-free cleanser and body wash and use warm but not hot water.

If your dry skin is caused by a skin condition such as eczema or psoriasis, you’ll need to treat the condition to see improvements. Visit your dermatologist for a targeted treatment plan.

If You Have Oily Skin …

“Oily skin has a shiny appearance, and it can feel greasy, particularly in the oil-rich areas of the face called the T-zone,” Hartman says.

You may also notice that you have larger pores. The more oil in your skin, the larger the openings tend to be, Hartman explains.

In addition, people with oily skin tend to be more prone to acne, as excess oil often contributes to clogged pores.

Genetics and hormones are the likely culprits when oily skin develops.

Those with oily skin should steer clear of oils and emollients (ingredients that form a film over your skin to seal in moisture).

 Instead, choose products that are gel-based, which provide a lightweight moisture.

 Some people may find that they don’t need a moisturizer at all.
If you opt for a moisturizer, Baumann recommends one with salicylic acid and retinol. Salicylic acid helps break down pimples and clears debris that can clog pores.

 Retinol is a form of vitamin A that boosts cell turnover to help keep skin clear.

Wash your skin with a gentle face wash twice daily and after sweating. Steer clear of harsh scrubs or alcohol-based cleansers, which can trigger your skin to ramp up oil production.

If You Have Combination Skin …

Combination skin is both dry and oily. You may notice that your skin is most oily in the T-zone because these areas have more oil glands, whereas your cheeks or jawline may be on the drier side, says Hartman. This can sometimes result in acne in the T-zone, though the location of blemishes and breakouts is individual.

To best treat combination skin, use products that target different areas of your face instead of smoothing products all over. For example, use products that are suitable for dry skin in the dry sections of your face and products designed for oily skin on the T-zone.

 For some people, that may include skipping moisturizer on oily areas of the face, such as the nose.

Moisturizers with ceramides are best for drier areas of the face, while products that contain salicylic acid or retinols are ideal for oily spots.

If You Have Sensitive Skin …

Sensitive skin is prone to irritation, redness, stinging, burning, and itching when exposed to stimuli that normally shouldn’t trigger a reaction.

Some people have sensitive skin because of genetic differences in the skin barrier (the outer layer of the skin that protects the delicate skin inner layers from harmful bacteria and chemicals).

 People with sensitive skin have a weakened skin barrier, which allows moisture to escape and allergens to enter into skin, making it more prone to reactions.

You’re more likely to have sensitive skin if you have certain skin conditions, such as eczema, psoriasis, acne, and rosacea.

You can also develop sensitive skin from skin-care products that cause irritation (such as retinols or retinoids) or allergic reactions, which temporarily weaken the skin barrier.

People with sensitive skin should opt for fragrance-free skin-care products. Some ingredients in products designed to address the signs of aging, such as retinoids or retinols, may cause irritation for sensitive skin.

 A dermatologist can help you choose products that align with these skin goals and provide advice on how best to apply them to minimize potential irritation.
Thicker moisturizers like creams and ointments seal in moisture. If you have sensitive skin due to a skin condition like eczema, look for ingredients in moisturizers like glycerin, hyaluronic acid, oats, or shea butter.

People with sensitive skin also benefit from doing a patch test before using any new skin-care products.

To do a skin patch test, apply a small amount of a new product to the inside of your arm daily for a week. Watch for potential skin reactions, such as redness or itching.

If your skin sensitivity is caused by a skin condition like rosacea, consult a board-certified dermatologist for advice on caring for your skin.

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What It Is, Function, Anatomy, and Diseases

With the right hormone balance, our bodies thrive. But sometimes our endocrine system creates too much or not enough of one of several hormones.

There are many reasons why this might happen. Endocrine gland dysfunction, family history of endocrine disease, stress, autoimmune conditions, and tumors can all disrupt hormone production and regulation, Zilbermint says.

There are hundreds of conditions tied to the endocrine system. Here are some of the more common ones.

Diabetes

Diabetes occurs when your blood sugar is too high. It happens when your pancreas doesn’t make enough (or any) insulin or doesn’t respond to the effects of insulin the way it should. As a result, your body doesn’t get enough insulin, and sugar builds up in your bloodstream instead of traveling to your cells to be used for energy.

There are three common types of diabetes.

  • Type 1 Diabetes If you have type 1 diabetes, your body is unable to make the insulin it needs to move glucose into your cells. This occurs because the immune system mistakenly destroys the cells in the pancreas that make insulin. Type 1 diabetes is an autoimmune condition and must be treated with insulin daily.
  • Type 2 Diabetes In type 2 diabetes, your body is unable to properly use the insulin your pancreas makes. It’s the most common type of diabetes and can appear at any age. Type 2 diabetes tends to occur in people with overweight or obesity and a family history of the disease. It can sometimes be managed with medications and lifestyle changes like a healthy diet and regular exercise. Sometimes it requires treatment with insulin.
  • Gestational Diabetes This type of diabetes develops only during pregnancy. It occurs when your body is unable to meet your increased demands for insulin. Gestational diabetes can often be treated with medications and lifestyle changes, but sometimes requires insulin.

Thyroid Disease

Thyroid disease is an umbrella term for medical conditions that develop when the thyroid makes too much or too few hormones.

There are two main types of thyroid disease. They are:

  • Hyperthyroidism Hyperthyroidism, also called overactive thyroid, happens when the thyroid releases too much thyroid hormone, causing your metabolism to speed up. This leads to symptoms such as increased sweating, shakiness, anxiety, unexplained weight loss, rapid heart rate, diarrhea, and difficulty sleeping (insomnia). The condition can be treated with medications, and, occasionally, surgery.

  • Hypothyroidism Hypothyroidism, also called underactive thyroid, occurs when the thyroid doesn’t release enough thyroid hormone. This causes your metabolism to slow down, leading to unexplained weight gain, fatigue, brain fog, depression, anxiety, muscle weakness, and cold intolerance. The condition is usually treated with medication to replace your natural thyroid hormones.

Cushing Syndrome

Cushing syndrome (hypercortisolism) occurs when the body has too much of the stress hormone cortisol. While rare, Cushing syndrome most commonly affects children, teenagers, and adults between ages 25 and 50. It can be caused by glucocorticoid medications (which are used to treat autoimmune diseases) or tumors in the endocrine glands.

Addison’s Disease 

Addison’s disease, also called adrenal insufficiency, is a rare disease that happens when the adrenal glands become damaged, often due to an autoimmune disease. This damage impacts the adrenal glands’ ability to make cortisol and aldosterone, causing symptoms such as fatigue, weight loss, low blood pressure, low blood sugar, muscle and joint pain, nausea, and irritability.

Polycystic Ovary Syndrome 

Polycystic ovary syndrome (PCOS) occurs when the ovaries produce high amounts of androgens, which include male sex hormones like testosterone. This causes the female reproductive hormones to become imbalanced, leading to irregular menstrual cycles, missed periods, and even infertility. PCOS is also associated with insulin resistance (when the body doesn’t respond to insulin the way it should) and obesity.

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Is BMI Accurate? What Body Mass Index Can and Can’t Reveal

BMI has long been a staple in health assessments. However, it is far from perfect, and as the years have passed, more and more science has emerged that reveals the flaws of this approach.

BMI Is an Inaccurate Way to Predict Disease Risk

BMI is inconsistent when it comes to accurately predicting the impact of body fat on disease risks or coexisting conditions.

For example, a study of postmenopausal women that calculated body fat percentage and risk by using age and sex in addition to height and weight was superior to BMI in accurately estimating the breast cancer risk linked to obesity.

BMI also doesn’t identify where fat is distributed in the body. Visceral fat, meaning fat deposits located around the abdomen and distributed throughout the organs, is more highly associated with diseases such as type 2 diabetes and heart disease, compared with other kinds of fat.

Visceral fat can be estimated with a simple tape measure and is used in assessments such as the body roundness index and waist-to-hip ratio.

BMI Can Misclassify Muscular People as Having Obesity

Although a high BMI is associated with having a high amount of body fat, BMI doesn’t directly measure body fat percentage.

“BMI is essentially a surrogate for adiposity or percent body fat, which is the actual risk factor,” says William Yancy Jr., MD, internal medicine doctor and obesity medicine specialist at Duke Health in Durham, North Carolina.

“Because BMI can’t differentiate between fat and muscle, it can misclassify very muscular people as overweight or obese,” Dr. Yancy says.

Two examples: The clearly fit and muscular USA rugby star Ilona Maher revealed she had a BMI of 29.3 in a TikTok video that has more than 1.2 million views.

When Arnold Schwarzenegger was crowned the Mr. Universe of the bodybuilding world, he also had a BMI of around 30, which would be in the “obesity” category, says Dr. Mehal.

“Clearly, his weight was due to muscle — he had very little body fat. But that’s the rare exception in today’s world. For most people who have a high BMI, it’s because they carry too much adipose tissue,” he says.

BMI can also underestimate risk in people with very low musculature, such as people with sarcopenia (a type of muscle loss that happens with aging or immobility), says Yancy.

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The Truth Behind 8 Common Myths About Food Allergies in Children

Whether your child was recently diagnosed with a food allergy or has been living with one for years, you know how stressful it can be to manage.

More and more are being diagnosed with allergies: The number of children with food allergies grew by 50 percent between 2007 and 2021.

As food allergies abound, so do misconceptions about them. Some myths can be dangerous, such as thinking Benadryl is just as good as an epinephrine auto-injector (EpiPen) when it comes to stopping an allergic reaction. (Spoiler: It’s not.)

To keep your child safe, it’s important to know all the facts around food allergies. Here are the truths behind some of the most common myths.

Myth 1: Food Allergies Aren’t That Serious

Food allergies can be deadly.

They’re more than just a mild irritation to certain foods. “Food allergies can lead to a severe, potentially life-threatening reaction called anaphylaxis, where your body goes into shock,” says Amanda Lee Pratt, MD, a pediatric allergy and immunology specialist at Duke University School of Medicine in Durham, North Carolina.

With anaphylaxis, blood pressure drops and the airway narrows, making it difficult to breathe. Some children get a skin rash or hives, while others become nauseous and vomit. If it isn’t treated right away — with an injection of epinephrine — it can be deadly.

Myth 2: All They Need Is Benadryl, Not an EpiPen

Antihistamines, such as diphenhydramine (Benadryl), do not stop anaphylaxis.

Epinephrine is “the first line of treatment,” says Christopher Codispoti, MD, an allergy and immunology specialist at The University of Texas Health Science Center in Houston. For a severe reaction, epinephrine — usually in the form of an auto-injector, such as an EpiPen — is needed, because it can quickly treat the symptoms of anaphylaxis. It opens the airway, making it easier to breathe, and helps regulate blood pressure and heart rate. It can also help reduce itching and hives.

“Antihistamines can be used as a supplement for more mild symptoms,” he says, “like a runny nose or itchy mouth.”

Myth 3: Eating a Little Bit of the Food Won’t Be Harmful and May Lessen the Allergy

Even a tiny amount of a food allergen can cause anaphylaxis.

You should help your child avoid all contact with the food. “Their body can still detect the allergen and have a reaction even in small amounts,” says Dr. Codispoti.

The only time your child should be intentionally exposed to the allergen is under the supervision of a doctor. You or your child should never do this on your own. Known as oral immunotherapy, it involves slowly exposing someone to their allergen in small doses to train their immune system not to have a reaction.

Myth 4: Food Intolerances and Food Allergies Are the Same

Food allergies and intolerances are very different. Food intolerances can be uncomfortable, but they are usually not life threatening.

“A food allergy is an antibody-mediated immune reaction to food that could lead to life-threatening symptoms,” Dr. Pratt explains. A food intolerance may or may not involve an immune system reaction and usually causes more mild symptoms, such as gastrointestinal issues, headaches, or skin problems.

Myth 5: Food Allergy Tests Are Always Accurate

Skin-prick and blood tests for food allergies can give false-positive results.

When it comes to diagnosing food allergies, the gold standard of testing is an oral food challenge, says Pratt. “We do it to see what happens when [your child puts] the food in question in [their] mouth,” she explains.

Here’s how it works: Under their doctor’s supervision, your child would eat the suspected food in measured doses, and the doctor would wait and watch for a reaction. If your child were to start having symptoms, the doctor would end the food challenge and give them medication to stop the reaction and relieve their symptoms.

Myth 6: Food Allergies Always Begin in Childhood

Food allergies can develop at any age, anytime.

“I’ve diagnosed people in their 70s and 80s,” Codispoti notes. The most common food allergies in adults are fish, shellfish, peanuts, and tree nuts.

Myth 7: Your Child Will Always Have Their Allergy

It’s possible that your child will outgrow their food allergy.

Children are more likely to grow out of certain allergies. “Around 80 percent of children who are allergic to eggs and milk will outgrow it,” says Pratt. “Peanuts and tree nuts are the opposite: Only 20 percent of children outgrow those.” The younger your child was diagnosed, the more likely they are to grow out of their food allergy, she notes.

Myth 8: If an Ingredient Isn’t Listed on a Restaurant Menu, It’s Safe to Eat

Not all ingredients are disclosed in the menu description, so you have to be extra careful when eating out.

Be sure to ask the server or manager not only for a list of every ingredient in the dish, but also exactly how it’s prepared. “You need to be cautious of cross contact during preparation in the kitchen,” says Codispoti.

Let the waitstaff know about your child’s food allergy, so they can accommodate you. To be even more prepared, go online and check out the menu ahead of time, so you can see what may be safe for your child to eat.

The Takeaway

  • Food allergies in children are on the rise.
  • Food allergies can be life threatening. It’s important to always have your child’s epinephrine medication on hand in case of a reaction.
  • Your child may eventually outgrow their food allergy, especially if it’s an allergy to milk or eggs.

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6 Health Issues to Watch for if You Have Hidradenitis Suppurativa

While there is still a lot to learn about HS, it is known that it can increase your risk of other potentially serious health issues. Here are six major ones to be aware of:

1. Metabolic Syndrome

HS appears to be linked to a higher risk of metabolic syndrome, a cluster of conditions — high blood pressure, excess body fat around the waist, high blood sugar, abnormal cholesterol or triglycerides — that often occur together.

 According to an analysis of studies, there is a strong association between HS and metabolic syndrome.

Left unmanaged, metabolic syndrome can increase your risk of heart attack and stroke. While there are many ways to address metabolic syndrome, making lifestyle changes, such as eating a healthy diet and increasing exercise, may help reduce the risk of serious complications.

2. Axial Spondyloarthritis

This type of arthritis mainly affects the axial skeleton — the chest, spine, and pelvis — though for some it can affect the digestive system, skin, and eyes.

 Research has indicated that HS may be more common in those who also experience this condition. One study of axial spondyloarthritis patients found that HS was more prevalent in that group compared with the general population.

The main symptom of axial spondyloarthritis is pain in the lower back.

 Treatment for the condition varies but may include medication, physical therapy, exercise, and lifestyle modifications.

3. Inflammatory Bowel Disease

Otherwise known as IBD, inflammatory bowel disease is an umbrella term used for disorders that involve chronic inflammation of the digestive tract. The two main types are ulcerative colitis and Crohn’s disease.

People with IBD may experience diarrhea, rectal bleeding, abdominal pain, weight loss, and fatigue, and treatment may require medications, nutritional support, and, in some cases, surgery.

A comprehensive review of large-scale studies found a significant association between HS and the risk of IBD in patients. Based on their findings, the study authors suggested that people with HS who experience recurrent symptoms like diarrhea, bloody stool, and abdominal pain see a gastroenterologist.

4. Cardiovascular Disease

Heart disease is the leading cause of death in the United States: One person dies every 33 seconds from it, according to the Centers for Disease Control and Prevention (CDC).

There are many forms of heart disease and causes of cardiovascular-related death, but research has shown that HS is associated with significantly increased risks of adverse cardiovascular-related outcomes, such as stroke, heart attack, and death.

 In a study, researchers found that having HS significantly increased the risk of heart attack or stroke.

Heart disease treatment varies widely from case to case, but lifestyle modifications and medications may be necessary, as well as medical procedures or surgeries in some cases.

5. Depression, Anxiety, and Suicide Risk

Skin disorders that cause visible symptoms can take an emotional toll and contribute to low self-worth, embarrassment, and social isolation. This, in turn, may increase risk for anxiety, depression, and suicidal thoughts and generally affect quality of life.

One research analysis found that depression and anxiety are common in people with HS. Given this link, the researchers recommend that clinicians watch for symptoms of mental health conditions that can accompany HS and refer patients for appropriate care.

6. Sexual Dysfunction

There are many forms of sexual dysfunction, but the term generally applies to any problem that prevents a person or couple from experiencing satisfaction from sexual activity.

According to one study, about half of people with HS experience sexual dysfunction. The research indicated that being in a stable relationship seemed to protect women with HS from developing sexual dysfunction and suggested that the issue may be partially related to extreme pain, active lesions, and other symptoms.

Treatment for sexual dysfunction depends on the cause and circumstances because both physical and psychological factors may be at play, but medications and psychotherapy may be helpful.

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Recognizing Early Psoriasis Signs: Symptoms, Triggers, and Treatment

The early signs and symptoms of psoriasis, and which parts of the body it affects, depend on the type. It is possible to have more than one type of psoriasis occurring at the same time.

Plaque Psoriasis

The most common type of psoriasis, plaque psoriasis accounts for 85 to 90 percent of cases.

Plaque psoriasis usually begins as small bumps on your skin. These bumps grow in groups and can form anywhere on your body, but most often affect the scalp, face, elbows, back, and knees.

As the condition progresses, the bumps form plaques, which are patches of thick skin covered in a silvery-white coating called scales. The color of the patches depends on the color of your skin; they’re typically red or pink on white skin and shades of purple with gray scale on darker skin.

The plaques are often initially round or oval and can connect to form larger plaques. They also are itchy, burning, or even painful, and the scales flake off easily. Scratching the plaque can cause it to flare up with inflammation and to bleed, potentially leading to dangerous infections.

The plaques also flare up in response to specific environmental triggers, ranging from stress to dry air to certain infections — this is another sign you may have plaque psoriasis instead of a simple rash or other skin condition.

Guttate Psoriasis

If instead of scaly patches you suddenly develop small, scaly red dots or lesions on your torso, back, or limbs, you may have guttate psoriasis. Be on the lookout for these symptoms if you have strep throat, which is guttate psoriasis’s most common trigger.

Typically appearing in children to young adults, guttate psoriasis often disappears completely after a few weeks, but some people with it go on to develop plaque psoriasis.

Inverse Psoriasis

You may have this type of psoriasis if you develop smooth, red patches of inflamed skin in the moist folds or creases of your skin, such as in your armpits or groin, under your breasts, or between your buttocks. The patches can be painful and contain cracks or fissures that are itchy or smell bad (or both).

Another sign you have inverse psoriasis is if these patches get worse from friction or sweat.

Nail Psoriasis

Psoriasis can affect your fingernails and toenails, too. You may have nail psoriasis if one or more of your nails starts becoming:

  • Pitted with little dents
  • Discolored
  • Rough and crumbly
  • Separated from the nail bed
  • Spotted with blood underneath

Nail psoriasis is common in people with plaque psoriasis, but it can also develop on its own.

Psoriatic Arthritis

If you have psoriasis, especially if it’s severe, make sure to pay attention to how your joints feel, as you have an increased risk of developing psoriatic arthritis. In fact, the majority of people who develop psoriatic arthritis already have psoriasis.

Look for these signs:

  • A painful, sausage-like swelling of a finger or toe, called dactylitis
  • Heel pain
  • Swelling in the area just above the heel
  • Joint stiffness in the morning

Pustular Psoriasis

In rare cases, psoriasis may present as non-infectious, pus-filled bumps called pustules, which are surrounded by red skin. The pustules are often localized to the hands and feet, but they may also spread to cover your whole body. The pustules usually break open and leak pus within a day, and after another day or two your skin will dry out and peel, revealing a smooth surface. The cycle may repeat itself after a few days or weeks.

Pustular psoriasis can be serious and life-threatening. If you have it, you will feel very sick and may develop:

  • Fever
  • Headache
  • Muscle weakness
  • Joint pain

Anyone with symptoms of pustular psoriasis should seek immediate medical attention.

Erythrodermic Psoriasis

If your psoriasis appears to be worsening or is unresponsive to treatment, it could be an early sign that you are developing erythrodermic psoriasis. This rare and life-threatening condition is marked by whole-body skin inflammation that’s severely itchy, red, and painful (it may look like the skin is burnt). Other symptoms such as chills, fever, and muscle weakness are also possible.

Anyone with symptoms of erythrodermic psoriasis should seek immediate medical attention.

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DMARDs for Ankylosing Spondylitis: Key Insights

Two groups of biologic treatments have been approved for AS, and others are in development.

TNF Inhibitors

One of the main drivers of inflammation in AS is a protein called tumor necrosis factor-alpha, or TNF-alpha. TNF-alpha is a type of cytokine, a small protein that plays a large role in mediating acute and chronic inflammation by signaling the immune system to get to work.

TNF-alpha and other cytokines bind to specific receptors on cells, stimulating the production of other immune system cells — including other inflammatory cytokines — and blood cells. But TNF-alpha is overactive in people with AS, causing significant inflammation.

TNF-alpha inhibitors, also known as anti-TNF therapies, are a type of biologic that neutralize TNF by blocking its signaling pathways, reducing inflammation and joint damage. Each TNF-alpha inhibitor works in a slightly different manner, so some may work for you while others do not. Anti-TNF drugs approved for ankylosing spondylitis include:

  • Infliximab (Remicade)
  • Etanercept (Enbrel)
  • Adalimumab (Humira)
  • Certolizumab pegol (Cimzia)
  • Golimumab (Simponi)
Because TNF-alpha inhibitors dampen part of the immune system, they can increase your risk of developing potentially serious infections and decrease your ability to fight infections. They may also slightly increase your risk of certain cancers, most notably lymphoma and skin cancers.

IL-17 Inhibitors

Another major contributor to inflammation in ankylosing spondylitis is interleukin-17 (IL-17). Like TNF-alpha, IL-17 is a type of cytokine that signals specific immune cells to activate inflammation. Similar to anti-TNF drugs, IL-17 inhibitors work by binding to the protein and blocking its activity. The medications carry similar risks as TNF inhibitors, and they may additionally exacerbate or cause inflammatory bowel disease (IBD).

Two IL-17 inhibitors approved for AS, both of which target the IL-17A cytokine variety, are:

  • Secukinumab (Cosentyx)
  • Ixekizumab (Taltz)

A third IL-17 inhibitor, which inhibits both the IL-17A and IL-17F cytokine varieties, is:

  • Bimekizumab-bkzx (Bimzelx)
The FDA approved bimekizumab for AS in September 2024.

Other Emerging Biologics

Research is ongoing to develop even more effective biologic treatments. For instance, brodalumab (Siliq) is a biologic that targets IL-17 receptors, offering a new approach to reducing inflammation. Rather than blocking specific IL-17 proteins, brodalumab binds to the IL-17 receptor A (or IL-17RA) on cells, preventing various IL-17 proteins — IL-17A, IL-17F, IL-17A/F, IL-17C, and IL-17E — from doing so and starting their individual inflammatory cascades.

Brodalumab is currently approved for treating plaque psoriasis, and research suggests it’s effective for a form of arthritis called axial spondylarthritis (ankylosing spondylitis falls under the axial spondylarthritis umbrella).

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