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Tuberculosis: Drug-defying global scourge

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COVID-19 may dominate tuberculosis (TB) as the world’s deadliest disease, but it continues to reject vaccines and antibiotics to cause serious harm to the world.

Here are five things you should know about tuberculosis that has plagued the world for thousands of years, ahead of World Tuberculosis Day on Thursday.

40,000 years

TB first appeared about 40,000 years ago, he said molecular analysis.

For a long time, scientists believed that tuberculosis in humans originated from tuberculosis in cattle, and it was spread when it was spread. animal husbandry began in the Neolithic Age.

But recent research has shown a different picture, which shows that tuberculosis already existed in humans before they started raising cattle. Symptoms of the disease were detected internally the rest of the people that is almost 11,000 years.

100 years ago: Vaccination

World Tuberculosis Day is celebrated every year on March 24, the day of the discovery of bacillus in 1882 by German Nobel laureate Robert Koch.

It was not until 1921 that the French Pasteur Institute developed the Bacillus Calmette-Guerin (BCG) vaccine, making it one of the oldest and most trusted jabs in the world.

For hundreds of years, the drug has been used and is particularly effective in preventing tuberculosis in children, but the effect is changing in adults.

Antibiotics are not very effective

In the 1940s and 1950s, the discovery of streptomycin and other antibiotics allowed for the treatment of lung tuberculosis, a type of disease most commonly known among adults and adolescents.

But a drug-resistant form of tuberculosis has emerged, which has forced doctors to use anti-bacterial cocktails to crush the bacteria effectively and to use their medication for several months.

Some species tolerate multiple tuberculosis drugs, forcing the use of alternative therapies for several months and causing recurrent failure in some cases.

Second-generation killer

TB is the second deadliest disease in the world after COVID-19 in 2020 (last year according to statistics), which caused 1.5 million deaths, according to the World Health Organization (WHO).

COVID-19 killed more than 1.8 million people that year, according to AFP figures.

Before COVID came out, tuberculosis took the lead, killing more people than HIV / AIDS, which killed 680,000 people by 2020, according to UNAIDS.

Tuberculosis is also a leading cause of death among people living with HIV.

Disruption of access to health care due to COVID has led to decades of progress toward treatable disease.

As a result, tuberculosis is on the rise again, with the death toll rising by 7% by 2020.

On five continents

Tuberculosis is endemic on all five continents, but developing countries are suffering from inequality.

By 2020, two regions have the highest number of new cases: Southeast Asia received 43 percent of new cases and Africa 25 percent, according to the WHO.

Two-thirds of the cases have increased in eight countries including Bangladesh, China, India, Indonesia, Nigeria, Pakistan, the Philippines and South Africa.


WHO bells ring for TB support


© 2022 AFP

hint: Tuberculosis: The World’s Drugs (2022, March 23) Retrieved 23 March 2022 from https://medicalxpress.com/news/2022-03-tuberculosis-drug-defying-global-scourge.html

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