Health

Scientists prove that inhaled vaccines offer better protection and immunity than nasal sprays

Michael D’Agostino demonstrated the method of air delivery, in which the study was conducted on a variety of animals. Credit: McMaster University

Scientists at McMaster University who have compared the delivery system for airway vaccines have proven that air injections provide better protection and protection than nasal sprays.

As the nasal passages reach the nose and throat, the inhaled air surrounds the nasal passages and delivers antibodies deep into the airways, where they can create great protection. immune responsethe researchers reported.

For the study, published online in the journal Next in ImmunologyThe researchers used tuberculosis vaccines to compare delivery methods by measuring the distribution of droplets, immune response and strength in animals.

When the drug is delivered directly into the lungs, it strengthens the immune system, providing the best protection against tuberculosis.

“Infectious diseases in upper respiratory tract tend to be mild. In the context of infections caused by viruses such as the flu or SARS-CoV-2, it is usually when the virus enters the lungs that it seriously affects you, “said Matthew Miller, lead author of the study. Canadian Study in Cancer at McMaster University.

“The antibiotics you produce when you deliver the medicine in depth lung is stronger than when you just put this substance in your nose and throat because of the physical and tissue conditions, and the immune system available to respond is very different, ”said Miller, who is also a researcher with Global Global Canada. Nexus for Diseases & Threats, based on McMaster.

Overall: Scientists have proven that inhaled vaccines provide better protection and immunity than nasal sprays.

Zhou Xing is a researcher and professor at the McMaster Center for Immunology and Medicine. Credit: McMaster University

“This study, for the first time, provides strong evidence to support the development of airway ventilation through nasal sprays for the prevention of respiratory infections including tuberculosis, COVID-19 and influenza,” said Zhou Xing. , research fellow and Professor at the McMaster Institute of Immunology and the Department of Medicine.

More than 6.3 million people died during the COVID-19 outbreak, and respiratory infections have been a major cause of illness and death worldwide, with urgent and renewed global efforts to improve access to vaccines being delivered directly to the mucous membrane of the earth. I breathe clearly.

Scientists at McMaster, who invented a unique form of inhaled COVID injection, believe this advanced delivery method provides the best protection against current and future diseases.

IN Stage 1 clinical trials It is currently in the process of evaluating aerosol inhaled in healthy adults who have previously received two or three doses of COVID mRNA.

It has been shown that nasal flu prevention is very effective in children, but they are not very effective in adults, leaving the flu vaccine as the most popular option for seasonal flu prevention.

Previous research by the McMaster team has shown that in addition to injection and pain relief, inhaled medicine is very effective in attacking the lungs and upper respiratory tract so that it can have greater protection with fewer doses. and injections.


The newly developed vaccine provides great protection against SARS-CoV-2, a variant


Its formation
McMaster University

hint: Overall: Scientists have proven that inhaled vaccines provide better protection and immunity than nasal sprays (2022, June 10) returned 10 June 2022 from https://medicalxpress.com/news / 2022-06-scientists-inhaled-vaccines- nasal.html

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Scientists prove that inhaled vaccines offer better protection and immunity than nasal sprays Source link Scientists prove that inhaled vaccines offer better protection and immunity than nasal sprays

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