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Reducing strokes caused by tiny air bubbles entering blood stream during heart surgery

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Researchers from the University of Bristol are studying how to reduce strokes and other brain problems after heart surgery, which can cause small air bubbles to leave the bloodstream after a heart attack. These small air bubbles block blood from reaching the brain.

Stroke is one of the worst conflicts to follow heart surgery, but it is difficult (almost one in 100 people undergo heart surgery). Most commonly (almost one in two people who have had heart surgery), people notice small changes in their thinking — most of these are short-lived, but some may last a long time.

It is thought that placing carbon dioxide near the heart during surgery can reduce the amount of air bubbles entering it. blood flowsince carbon dioxide dissolves in the blood more easily than air.

Research by Drs. Led by Ben Gibbison and researchers from the Bristol Heart Center and the Bristol Experimental Center, they set out to find out if this is true, and how effective it is.

In this study, researchers will compare carbon dioxide with medical air to see if it is effective in reducing blood pressure. The medical air is the same as the air around us and has no effect, nor is the absolute placebo for CO.2 apprenticeship.

The researchers will allow 704 participants from across the UK who undergo open heart surgery to receive either carbon dioxide or iskar doctor (placebo). Not a participant, surgical team whether the research team will know which intervention is taking place.

The study was launched in October 2021 and is expected to yield results by April 2024. If CO2 has been shown to be effective and can have a significant impact on the outcome of heart surgery, with the potential for increased risk number of survivors and quality of life for people following surgery.

Dr. Gibbison, a senior consultant in cardiology and intensive care at the University of Bristol, says: “If you come to a heart surgeon right now, you have a 50 per cent chance of getting CO2 in weakness. This study will tell us if it is effective and everyone should use CO2 or it does not work and we do not use it. ”


A positive risk factor from cardiac surgery results in better patient outcomes


Learn more:
Rachel Todd, CO2 Study: Carbon dioxide deficiency and brain damage during cardiac surgery, (2020). DOI: 10.1186 / ISRCTN30671536

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University of Bristol

hint: Reduces strokes caused by small bubbles entering the bloodstream during cardiac arrest (2022, April 14) Retrieved 14 April 2022 from https://medicalxpress.com/news/2022-04-tiny-air-blood -stream-heart.html

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