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Plaque-lined arteries put future health of young American Indians at risk

Young American Indians with early signs of plaque in their arteries may be particularly vulnerable to heart attack, stroke, and other cardiovascular disease later in life, according to a new study calling for early intervention.

Atherosclerosis is a common and potentially dangerous condition because it diminishes Blood flow Wherever plaque occurs, whether it is in an artery heart, Brain, legs or kidneys. Plaque can also enter the bloodstream and get stuck in other parts of the body.

Researchers have paid particular attention to asymptomatic atherosclerosis. This means that this condition has not yet caused symptoms. They wanted to see how common it was to young American Indians, an unstudied population, and how it would affect their future cardiovascular health.

They examined 1,376 American Indians between the ages of 14 and 39 participating in the Strong Hart Family Study. At the beginning of the study, they had no signs of cardiovascular disease. Using ultrasound of the carotid artery of the neck, 71 participants (5.2%) were found to have asymptomatic atherosclerosis.During the follow-up period of about 18 years, 120 people (8.7%) heart attack, Stroke or other cardiovascular disease.

After controlling Risk factor Researchers, such as age and obesity, found that participants who started their studies with asymptomatic atherosclerosis had an 85% risk of developing or dying from cardiovascular disease compared to those who did not. I found it expensive. In other words, the frequency of cardiovascular events in patients with asymptomatic atherosclerosis was 13.5 per 1,000 person-years, with 1,000 cases lasting for one year. This is compared to 5 unconditional people per 1,000 man-hours.

The results were not surprising, but it was worrisome to see so many Native American teens and young adults showing early signs of atherosclerosis, Jessica, lead author of the study. Dr. Reese said.

“Heart disease begins early in this population and causes (cardiovascular disease) events later in life. It’s a really good idea for doctors to start screening programs early.” Cholesterol and High blood pressure, Even a teenager, Reese said. She is an assistant professor at the American Indian Health Research Center at the University of Oklahoma Health Sciences Center in Oklahoma City.

The study was presented this weekend at the American Heart Association’s Virtual Science session. Findings are considered preliminary until published in a peer-reviewed journal.

Few studies have examined teenage arterial plaques, so it’s unclear how these findings will be compared to teens of other races and ethnicities, Reese said.

“It’s based on vigorous research that helps us understand the heart health of American Indians, who are particularly prevalent in cardiac metabolic disorders,” said Spero Manson, who wasn’t involved in the study. Stated.

He said research is needed to learn which early precautions are most effective and why. Early screening for cholesterol, blood pressure, and other cardiovascular risk factors is important, he said, but exercise and diet are also important. Healthy dietThis can be particularly difficult for many Native Americans due to social barriers and historical lack of investment.

“Unfavorable diets, from sugar drinks to high-carbohydrate and high-fat foods, are not just a function of personal preference. They lack healthy foods in the dietary deserts of many rural and booking communities. That’s the result, “Manson said. He is a professor of public health and psychiatry at the University of Colorado Anschuts Medical Campus in Aurora and a director of the American Indian and Alaskan Native Health Centers.

Despite the world’s focus on the COVID-19 pandemic, Manson said, “The tribal community is still keeping an eye on chronic conditions such as obesity and cardiac metabolic status and complacency. We need to be unsatisfied. We have to create a lifestyle, and change behavior and maintain them in the long run. ”


Over 40% of adults with no known heart disease had fat deposits in the heart arteries


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