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Pfizer booster study lifts mood over Omicron variant

Palestinian medics prepare doses of the Pfizer / BioNTech Covid-19 vaccine.

Three doses of Pfizer-BioNTech coronavirus vaccine appear to be effective against Omicron mutants. This is promising news, even if Denmark and the UK have announced new limits to curb the surge in cases.

In preliminary results released Wednesday, US and German companies behind the world’s leading shots to fight COVID-19 are the same boosters seen after the second dose on the first strain. He said he produced a strong antibody against the level of Omicron.

However, they warned that “Omicron variants are probably not sufficiently neutralized after two doses.”

This announcement, which has not yet been peer-reviewed, is called Reassurance by experts and came when the first independent data from laboratories around the world emerged. This shows that new mutations are better at avoiding infections and immunity from vaccines than before.

“We still need to be highly measured and wait to see the approach, but I think we have at least encouragement,” said Angela Rasmussen, a virologist of Canadian vaccine and infectious disease organizations. I told AFP.

Blood samples from about 20 people who received the current vaccine twice showed an average reduction in neutralizing antibodies by an average of 1/25 compared to the early strains of the virus, the two companies said.

However, they added that another part of the immune response (from T cells) was probably still effective against the new mutant.

Vaccine makers are developing an Omicron-specific version of the jab and hope to be ready by March, but said the decision on mass production will depend on the spread of variants.

British Prime Minister Boris Johnson Johnson

British Prime Minister Boris Johnson Johnson is harsh in the face of public anger at the video footage of his aides joking about an allegedly illegal Christmas party on Downing Street during the blockade last year. Announced measures.

New restrictions

In Europe, Danish Prime Minister Mette Frederiksen has announced that he will encourage citizens to work from home to extend Christmas holidays, reduce nightlife and combat the outbreak of infections.

“We have no plans for a long-term closure,” she said, but admitted that returning to the home office would not be welcomed by many.

Her UK counterpart, Boris Johnson, also brought back guidance for working from home and vaccine passports for venues such as nightclubs and stadiums. The new measures have been applied to England and have already been implemented in Scotland and Wales.

“We must be humble when faced with this virus,” he added, adding that “moving to Plan B in England is proportional and responsible.”

Johnson has announced rigorous steps in the face of public anger at the video footage of his aides joking about the illegal Christmas party in Downing Street during the blockade last year.

Meanwhile, WHO Chief Tedros Adhanom Ghebreyesus summarized what scientists have learned about Omicron since it was first reported in South Africa in late November.

He said it could successfully circumvent previous immunity and cause milder illness.

However, even if it is confirmed to be less serious, the increased transmission rate of this variant is believed to be greater than the currently predominant Delta strain, which can make many people sick. ..

Coronavirus mutant

Fact file about what you know about the Omicron coronavirus variant so far. Pfizer / BioNTech said on December 8 that three doses of the vaccine should be “effective” against mutations.

Three shots

Pfizer and BioNTech news show that other preliminary results from a small study in South Africa show that antibodies from the same vaccine are up to 40 times less capable of neutralizing Omicron compared to earlier strains. I came after suggesting that I did.

Willem Hanecom, secretary general of the African Institute of Health, who conducted the study, said the results only reflect the laboratory settings and the actual data are true tests, so the results are interpreted. He said it was important to be “very careful”.

Studies by German and Swedish researchers also showed a decrease in antibodies, but in varying sizes.

Omicron counts more than 30 mutations in the peplomer protein, which is scattered on the surface of the coronavirus and allows it to invade cells, and is widely expected for advanced antigenic escape.

However, the fact that boosters appear to restore high protection has been welcomed by many experts and “strongly supports the three-dose vaccination campaign,” said Charles Van, an immunological scholar at Imperial College London. Gum says.

Omicron’s positive initial rating helped to raise the mood in particular, Global market The emergence of variants emphasized that the fight against the pandemic is not over yet, as the fear of another recession has subsided.

COVID-19 has officially killed more than 5.2 million people worldwide since it was first declared in late 2019, but the actual number of casualties could be several times higher.


Pfizer / BioNTech refers to three “effective” doses for Omicron


© 2021 AFP

Quote: Pfizer Booster study was obtained from https://medicalxpress.com/news/2021-12-pfizer-booster-mood-omicron-variant.html on December 9, 2021 (December 2021). 9th) to raise the mood

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Pfizer booster study lifts mood over Omicron variant Source link Pfizer booster study lifts mood over Omicron variant

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