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New study finds higher rates of newly diagnosed type 2 diabetes after infection with mild COVID-19

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New research published in Diabetes (magazine of the European Association of Professional Sciences [EASD]), suggests a possible association between low COVID-19 cases and diagnosis of type 2 diabetes.

A study of health data from 1,171 general and local projects across Germany by Professor Wolfgang Rathmann and Professor Oliver Kuss from the German Center for Diabetes at Heinrich Heine University, Dusseldorf, Germany, and Professor Karel Kostev (IQVIA, Frankfurt , Germany) managed to find out that. Adults who recovered from low levels of COVID-19 appeared to have a higher risk of developing type 2 diabetes diabetes than the appropriate care team who have other types of respiratory illnesses, which are usually caused by viruses.

If confirmed, these results suggest that diabetes testing in humans after recovery from COVID-19 should be recommended, the researchers said. This potential link between COVID-19 and diabetes is also being investigated in various ongoing studies, including on COVIDiab registration and other studies related to so-called ‘long COVID’.

Previous studies have found that inflammation caused by SARS-CoV-2 can damage beta-insulin-producing beta cells, causing death or altering their function, leading to severe hyperglycemia (high blood pressure). Tissues that are less responsive to insulin due to inflammation in the body and are thought to be more likely to cause it. The off-the-shelf lifestyle brought by locks can play a role. This may explain why new-onset hyperglycaemia and insulin resistance have been reported in COVID-19 patients who have no history of diabetes.

However, it is not known whether these lifestyle changes are temporary or whether people with COVID-19 may be at increased risk for developing type 2 diabetes. In addition, there are limited studies investigating the diagnosis of diabetes after recovery from COVID-19 in low-risk conditions.

To provide further evidence, the researchers analyzed electronic health data from the Centers for Disease Control, which included data on 8.8 million adults who visited 1,171 general and domestic services across Germany between March 2020 and January 2021. includes 35,865 patients diagnosed with COVID -19. The incidence of diabetes mellitus after COVID-19 was compared with that of a group of men (average age 43; 46% women) who were found to have acute respiratory distress syndrome (AURI) (but not COVID-19) in simultaneously, corresponding to sex, age, health coverage, month index of COVID-19 or AURI diagnosis of diseases (obesity, high blood pressure, high cholesterol, heart attack, stroke). The retrospective model was used to quantify recurrence ratios (IRRs) for type 2 diabetes and other types of diabetes.

People with a history of COVID-19 or diabetes, and those who use corticosteroids within 30 days after the index days are removed. At an average follow-up of 119 days for COVID-19 and 161 days for AURI, the number of hospitalizations was the same in both groups (COVID-19: 3.2% vs control: 3.1%; average hospital stay: 1 in both. groups).

The researchers found that new cases of type 2 diabetes were more prevalent in patients who tested positive for COVID-19 than those with AURI (15.8 vs 12.3 in 1000 people per year). and the average incident rate (IRR) of 1.28. Simply put, this means that the risk of developing type 2 diabetes in the COVID group is 28% higher than that of the AURI group. The IRR of the COVID group was not increased in some unexplained forms of diabetes.

“COVID-19 can cause diabetes by regulating the body’s immune system after remission, which can lead to pancreatic beta deficiency and insulin resistance, or patients may be at increased risk of developing diabetes due to obesity or diabetes, stress COVID. -19 make their bodies faster “, says lead author Professor Wolfgang Rathmann. “The risk of abnormal blood pressure in people with COVID-19 is likely to be high, depending on risk factors such as injury. beta cellsan additional reference to inflammation, and changes in diseases associated with obesity and reduced mobility, ”said lead author Professor Oliver Kuss.

Professor Rathmann added: “Since COVID-19 patients have been followed for only three months, further follow-up is needed to understand whether type 2 diabetes after COVID-19 is temporary and will ‘They can move after they have fully recovered, or it can cause illness.’

Although type 2 diabetes may not be a problem for most people with mild COVID-19, the authors recommend that anyone recovering from COVID-19 be aware of warning signs and symptoms such as fatigue, high urine. , and increase thirst, and seek treatment immediately.

The authors note some limitations to their research, including brief descriptions of the hospital and individuals identified as having COVID-19 in the public domain (e.g. in hospitals or at COVID-19 testing centers) may limit the accuracy of the results. . Similarly, they were unable to control their body weight because no data were available and the incidence of type 1 diabetes was not investigated due to the small number. Finally, they realized that their research might not be as common to the general public.


The risk of diabetes increases for patients with COVID-19 pediatric patients


Learn more:
Wolfgang Rathmann et al, Diabetes diagnosed after Covid-19, Diabetes (2022). DOI: 10.1007 / s00125-022-05670-0

hintA new study has found the highest number of new cases of type 2 diabetes after simple COVID-19 infection (2022, March 16) was recovered on 16 March 2022 from https://medicalxpress.com/news/2022-03 -higher-newly-diabetes- infection-soft.html

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New study finds higher rates of newly diagnosed type 2 diabetes after infection with mild COVID-19 Source link New study finds higher rates of newly diagnosed type 2 diabetes after infection with mild COVID-19

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