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mRNA-based COVID-19 vaccines are safe for high-risk patients, shows study

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Think for patients who are weak during COVID-19 infection. Their condition puts them at serious risk of complications from COVID-19, but it also raises doubts about the safety and quality of vaccines that can protect them.

A new study at Frontiers in Oncology helps to put this 22-‘s immune system down by discovering that two popular mRNA vaccines are tolerant of such highly potent patients. The experiment found that vaccines were unhealthy and did not cause adverse events in a group of patients with various cancers, viruses, and rheumatological diseases that were associated with immunization. The results will reassure patients who are skeptical of prevention that the vaccines are safe, even for patients.

So far, many of us have been vaccinated against COVID-19, including those who rely on the latest mRNA technology, and this has allowed the community to reopen in many countries. Immunosuppressive therapy, coupled with increased Omicron diversity, means a higher prevalence of COVID-19 infections. severe disease has declined significantly over the past year. However, no one was allowed to drive in public.

Basic clinical trials of these vaccines were conducted in healthy volunteers. While this is true standard operationmeans that critically ill patients, such as those taking antibiotics for neurological conditions, are not included in the trial.

The latest 22-injections for critically ill patients

This lack of experimental data can lead such patients to doubt the safety and effectiveness of the vaccine. However, in a nutshell, they are also at high risk for COVID-19 complications, suggesting that they would benefit greatly from protection through prevention. In an effort to shed more light on the safety of COVID-19-based mRNA, a team of researchers in Italy conducted a study to assess the safety of COVID-19 in patients at high risk.

The researchers enrolled 566 patients in the trial, and administered two doses of either Pfizer-BioNTech or Moderna mRNA vaccine. Patients reported any adverse events in the questionnaire, and the interviews focused on the first week after each episode.

The most common side effects at the injection site include pain, swelling, and rash, while most general symptoms include fatigue, headache, chills and muscle aches. Similar side effects are also more commonly reported in people who have a fully developed immune system. The study also found that there was no evidence that the patient was affected, and that the vaccine did not prevent the patient from adapting to their condition.

There is no greater incidence of adverse events in my critically ill patients

“Surprisingly, we found that the incidence of adverse events in these high-risk patients was similar to that reported in immunization trials conducted in the general population,” said Professor Nicola Silvestris of Bari Aldo University. Moro, Italy, great writer.

“Our patients do not show the highest incidence of adverse events and do not see any risk of discontinuing treatment programs due to the vaccine. Therefore, COVID-19 vaccine has been proven to be safe. , even in this high-risk group. patients. “

The result will help to calm fear in between sick patients those who are at high risk for COVID-19, but are also concerned about illa-corruption of vaccine.

“Our main recommendation regarding the results of this study is that COVID-19 is highly recommended and the profile is encouraging,” said Drs. Maria Teresa Lupo-Stanghellini of the San Raffaele Science Center, Italy, lead author on the study. apprenticeship.

“We are moving forward relationship note COVID-19 prevention continues in the spirit of providing the best prevention and care for us patients. ”


Research recommends additional COVID-19 injections for patients who are not vaccinated


Learn more:
Safe and tolerant mRNA-COVID19 vaccine can be considered for debilitating patients, Frontiers in Oncology2022. DOI: 10.3389 / fonc.2022.855723 , www.frontiersin.org/articles/1… onc.2022.855723 / full

hintThe COVID-19 vaccine against mRNA is not safe for critically ill patients, shows study (2022, March 17) retrieved 17 March 2022 from https://medicalxpress.com/news/2022-03-mrna- based-covid-vaccines -safe-high-risk.html

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