Travis Coldwell CNN
Merck and Ridgeback Therapeutics said on Friday that the pills cut the risk of hospitalization or death from Covid-19 in half.
If approved by the US Food and Drug Administration for an emergency use authorization, it will be Covid-19’s first oral antiviral drug.
“In an interim analysis, molnupiravir reduced the risk of hospitalization or death by about 50%,” Merck said in a news release. “7.3% of patients who received molnupiravir were hospitalized or died until day 29 after randomization (28/385), compared to 14.1% (53,377) of patients who received placebo. No deaths were reported in patients receiving molnupiravir until day 29, compared to the deaths of 8 patients who received it. “
Merck said it would seek an emergency use authorization from the FDA “as soon as possible.”
Experts say that the development of oral antiviral drugs Maybe the next chance to stop Covid-19.. A short-term regimen of daily tablets aims to combat the virus early after diagnosis and prevent symptoms from appearing after exposure.
One antiviral drug Covid treatment approved.. Remdesivir is given intravenously to sick patients in hospitals. It is not intended for early widespread use.
Vaccinations are increasing in some states
Meanwhile, more states and health care systems Forced inoculation For certain workers, authorities want employment incentives to eliminate vaccine hesitation — while a governor prepares a scenario of contingency.
Connecticut Governor Ned Lamont has instructed the National Guard to prepare for a shortage of personnel when vaccine obligations and testing requirements come into force at the end of Monday, he said. State employees must submit a vaccination certificate or weekly inspection requirements by the deadline, and those who do not comply will be placed on unpaid leave.
As of Thursday, more than 63% (20,000 employees) had been fully vaccinated and 12% of employees had begun weekly testing, Lamont said. There are more than 8,000 non-compliant employees left, but about 2,000 have updated their status in the last two days.
“We offer employees in most states the option to take weekly tests instead of vaccination, giving them more flexibility than neighboring states, and employees have a compliance grace period. There is no reason why not all employees should comply, “says Lamont.
Connecticut is just one of several states facing a backlash against mandating important workers to vaccinate. This move has been highlighted by health professionals as needed to protect people at high risk for Covid-19, but a minority of voices wanting to maintain both unvaccinated and current roles.
Rhode Island’s Ministry of Health announced in August that “all RIDOH-licensed medical facility employees, internships, and volunteers” need to be first vaccinated with the Covid-19 vaccine by Friday. Did.
Care New England, one of the state’s largest hospital systems, reported Thursday that more than 95% of health care workers are vaccinated. According to System CEO James E. Fanale, staff vaccination “is increasing day by day and hour by hour.”
In other states the deadline has already passed.2 million healthcare workers in California I had to get vaccinated Tax exemption is available by Thursday or for religious beliefs or qualified medical reasons and you risk losing your job.
Many hospitals surveyed by CNN had high employee immunization rates, averaging over 90% in some of the state’s largest health systems.
In New York, no medical facilities were closed as a result of mandatory vaccinations for workers, Governor Kathy Hokul said Thursday. Earlier this week Reported 92% of nursing home staff, 89% of adult care facility staff, and 92% of hospital staff receive at least one dose throughout the state.
“We found that as more people were laid off or suspended, that number would increase, so you’ll see that number increase soon,” Hokur said. Said.
Some regional hospitals reported Employee suspension Without payment due to shortages or without temporarily suspending selective hospitalization procedures.
Vaccines aged 5-11 may be available soon, but polls show that hesitation remains
As Delta variants continue to spread, healthcare professionals are not the only ones dealing with everyday work risks. Resuming face-to-face learning at school is already complicated by the outbreak of Covid-19 and the isolation of exposed students and staff.
A new study found that vaccination among parents and guardians about vaccination of children aged 5 to 11 years, despite evidence that vaccination reduces Covid-19 infection and severity in eligible age groups. Still hesitates.
Only about one-third of parents between the ages of 5 and 11 say they will vaccinate their children as soon as the vaccine is available in that age group. according to Results of the Kaiser Family Foundation Vaccine Monitor announced Thursday. A similar percentage, 32%, said they would wait for the vaccine to work, and 24% said they would definitely not get the vaccine aged 5-11.
According to the report, 58% of parents say that all students and staff need masks in schools from kindergarten to high school, and 4% only need masks for unvaccinated students and staff. 35% said there was no mask requirement. ..
According to KFF, there is disagreement between vaccinated and unvaccinated parents, and 73% of vaccinated parents should require all students to wear masks. Yes, 63% of unvaccinated parents say they do not need a mask.
Most of the interviews conducted from a sample of more than 1,500 adults between September 13 and 22 found that Pfizer was safe in clinical trials with the Covid-19 vaccine and elicited an immune response in this age group. It was before the announcement.
The Pfizer / BioNTech vaccine has been approved for people over the age of 16 and has an emergency use authorization for people between the ages of 12 and 15.On Tuesday, Pfizer and BioNTech announced They submitted Data on children between the ages of 5 and 11 have been submitted to the FDA for initial review, but have not yet requested an emergency use authorization.
The two companies said in a statement that formal submissions requesting an EUA for the vaccine are expected to continue within the next few weeks.
Among those already covered by the vaccine Latest data Nearly 200 million US adults have been vaccinated at least once, according to a report from the US Centers for Disease Control and Prevention. Nearly 67% of adults in the United States are fully vaccinated.
Higher non-metropolitan mortality rates, studies find
Meanwhile, researchers are looking at the impact of pandemics on different parts of the country.
According to data analysis from the University of Iowa’s Center for Health Policy Analysis, Johns Hopkins University, Covid-19 mortality in non-metropolitan areas is now more than double the Covid-19 mortality rate in metropolitan areas. doing.
After analyzing data on average Covid-19 mortality at the county level, an average of 0.85 Covid-19 deaths per 100,000 inhabitants in the non-metropolitan area in the two weeks to September 15, 2021. It was determined that there was. The average for metropolitan areas is half that, with 0.41 Covid-19 deaths for every 100,000 inhabitants.
Since the start of the survey in April 2020, non-metropolitan mortality rates have consistently exceeded metropolitan mortality rates, and figures since September 15 show non-metropolitan mortality rates in metropolitan areas. This is the fourth time in total, which is at least twice the mortality rate of. However, since December 1, 2020, the proportion of non-metropolitan areas has not doubled that of metropolitan areas.
Researchers used the USDA methodology to distinguish between metropolitan and non-metropolitan areas. A county was recorded as a metropolis if it had an urban area with a population of 50,000 or more, or if it was a suburban county with strong economic ties to the city center. All other counties in the survey were coded as non-metropolitan.
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Merck says pill cuts risk of Covid-19 hospitalization, death in half as many states see vaccinations increase – San Bernardino Sun Source link Merck says pill cuts risk of Covid-19 hospitalization, death in half as many states see vaccinations increase – San Bernardino Sun