The monophasic Salmonella Typhimurium outbreak has been linked in 10 European countries with 150 reports, mostly affecting children, and chocolate products made by a large company. Since the discovery of the first chocolate cases in the UK in February 2022, one of the largest chocolate product shipments in European business history has taken place. Given the approach of the Easter holiday, the proliferation of products, and the vulnerability of the affected people, early and efficient sharing of pathogenic and pathogenic data has been an important factor in managing this devastating food crisis.
In the speed of communication published on Euro sa ido, Larkin et al. describe epidemiological studies and standardized measures in countries. In February 2022, a small cohort of five nucleotide polymorphism (SNP) colonies of eight cases of infection with the monophasic Salmonella enterica subsp. enterica serotype Typhimurium (1,4,5,12: i :-) eBG 1, type 34 (ST) was found in the UK. The collection is relatively new, with no cases reported less than 10 years of age, and the species exhibits signs of abnormal immune response in animals, food, or human diseases. in the UK. The collection has nothing to do with any other species of S. Typhimurium in the UK.
Research questions using open, non-binary yes / no question system were conducted to formulate perceptions, and then a targeted questionnaire was used to validate the ideas identified by research questions, confirms a strong signal to the specific chocolate mark. products.
Following the British announcement of the European Center for Disease Control and Prevention (ECDC) EpiPulse Food and Disease (FWD) on 17 February 2022, and the First Alert and Response System (EWRS) alert on 25 March, Germany, Sweden, France , The Netherlands, Luxembourg, Norway, Ireland, Belgium, and Spain have all reported confirmed cases of infection in their countries. On April 8, 2022, a total of 150 people were confirmed and identified as possible, with a sample date of the trial from December 21, 2021 (UK case) to March 28, 2022. Investigated of the epidemic indicates that the disease is more prevalent in young children. The clinical rate was 42% of cases reported, higher than the one commonly reported in salmonellosis outbreaks and for each individual infected with S. Typhimurium. While this is possible and affects the demographic characteristics of the victims, this is a possible sign of increasing the severity of the infection in this case. tear.
Food chain research in the affected countries shows that most of the products involved in diagnosing the disease are mostly made at a production facility in Belgium. This is where the type of outbreak was detected in December 2021 in the milk processing equipment.
Due to the strong evidence of pathogens causing these products in this outbreak, on the food web links identified and the disease evidence previously found in production, risk control measures have been taken in all affected countries. , including withdrawing all product lines generated in the detected objects. a wide range of production and memory products, supporting news alerts and recommendations for consumers, starting with the first memory on 2 April in the UK and Ireland and expanding to other countries soon thereafter. The appeal was also extended from April 7 while investigations are underway in several countries, resulting in more evidence to support the call. On April 8, Belgian authorities suspended production at the center in Belgium, and the WHO / FAO (INFOSAN) also issued a global alert on April 10 informing countries and 77 regions established for product distribution. to begin to remember the world.
Resistant profile and several drugs
Another interesting feature of the outbreak is the resistance to many anti-inflammatory drugs, especially resistance to kanamycin and gentamicin, and the presence of lnu (F), a specific resistance to lincosamides, which are less susceptible to monophasic S Typhimurium in Europe. . Outbreaks appear to be exacerbated by fluoroquinolones, azithromycin, and cephalosporins of the third century, which provide promising treatment options for leukemia, but abnormal AMR information provides additional features of the type of outbreak that all countries can assess at the initial stages. of research to confirm the phenomenon and the potential for speculation. This emphasizes the advantage of incorporating additional AMR data that is not known at the beginning of the international network and subsequent integration as part of a global disaster interpretation, where it makes it easier to identify probabilities before application -GGS and / or epidemiological research to confirm the outbreak.
Preliminary information on the detection of the outbreak and the initial findings of a UK study that follows the rapid collaboration between many countries in the exchange of information is critical to the rapid development of the outbreak study. The epidemiological data provides strong evidence related to the vehicle of infection, especially when combined at the national level, allows public health authorities and food safety agencies to implement their measures. fit quickly. Subsequent data on the detection of the type of explosion in the associated equipment in December 2021, provide further confirmation of the causal link between the company’s products and the European outbreak.
Larkin et al, International Monophasic Outbreaks Study of Salmonella Typhimurium Drug-Related Combinations with Chocolate Products, EU / EEA and United Kingdom, February to April 2022, Euro sa ido (2022). DOI: 10.2807 / 1560-7917.ES.2022.27.15.2200314. www.eurosurveillance.org/conte… S.2022.27.15.2200314
Provided by the European Center for Disease Control (ECDC).
hintThe most memorable chocolate products from the Salmonella Typhimurium outbreak in 10 European countries (2022, April 14) were recovered on 14 April 2022 from https://medicalxpress.com/news/2022-04-massive-recall-chocolate- products- because.html
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