Health

Excess weight almost doubles risk of womb cancer

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A recent study found that overweight life is almost double a woman’s risk of developing cervical cancer, according to a Cancer Research UK study published today in. BMC Medicine.

A study by the University of Bristol was one of the first to find that for every 5 percent of overweight BMI, a woman’s risk of endometrial cancer doubled (88%). ). This is more than most previous studies have suggested and reflects the status of life rather than a picture in time like other studies. Five BMI units is the difference between kiba type and type of obesity, or that of a 5-foot-tall, 5-inch adult being two stones (28 pounds) heavier.

The international study looked at genetic samples from nearly 120,000 women from Australia, Belgium, Germany, Poland, Sweden, the UK, and the US who had about 13,000 had cervical cancer. This large statistical study is one of the first studies of its kind to look at the impact of high BMI on longevity on cervical cancer risk.

The researchers looked at 14 character traits, which could include kiba and cervical cancer. They discovered two types of hormones — fast insulin and testosterone — that increased the risk of developing cervical cancer. By pointing out exactly how obesity increases the risk of cancer, as by hormones, scientists in the future may use drugs to reduce or increase the level of these hormones in people who are at risk of cancer. For example, drugs like metformin used in the treatment of diabetes may lower hormone levels and research has shown that this drug increases the risk of cancer, although it is still being studied.

Cervical cancer is one of the most common types of cancer associated with obesity. It is the most common cancer in low-income countries and the fourth most common cancer in women in the UK — 1 in 36 women diagnosed in their lifetime. And for those with cervical cancer in the UK, it is estimated that almost three per cent occur as a result of obesity and obesity.

Obesity is the second largest risk factor for cancer in the UK. It is estimated that more than one in 20 people with cancer in the UK are diagnosed with obesity.

Emma Hazelwood, co-author of the paper, said, “This study is an exciting first step in how genetic studies can be used to find out exactly how obesity causes cancer, and what can can be done to treat it.The link between obesity and stomach ache is. well known but this is one of the major studies that have examined why this is at the genetic level, we expect further research to find out how We can use this information to help reduce the risk of cancer in people who are obese. “

Dr Julie Sharp, director of public health at the British Cancer Research Center, said: “Cancer Research UK has been at the forefront of finding a link between obesity and cancer over the years. Such research reinforces the fact that obesity Obesity is the second leading cause of cancer in the UK and could help us begin to understand why this could play a key role in finding out how to prevent and treat cancer in the future.

“More research is needed to find out the exact treatments and therapies that can be used to treat cancer risk among people with obesity. We already know that obesity increases the risk of developing 13 different types of cancer. . To reduce the risk of cancer. ” “It is important to maintain a healthy weight by eating a balanced diet and staying active.”

The story of Kath

When Kath first started bleeding in 2013, she made it to the menopause. Despite her daughter’s need for a check-up, she continues to do the work she loves – working as a breastmilk at Debenhams Trafford. But before Christmas in 2013, she suffered from severe hemorrhage which prompted her to make an appointment with a doctor.

In January 2014, Kath went to her GP and was referred to the Royal Bolton Hospital where she underwent a biopsy. She was diagnosed with cancer.

“When you heard the word cancer your mind was aroused, and I thought, ‘Will I live to see my grandchildren grow up?'” Said Kath.

“I felt so sick I didn’t know what was going on. It was as if in a dream I was upset when I found out I was crying and my husband was holding my hand.”

Thankfully, Kath’s cancer was diagnosed at an early stage, which means she may have to undergo life-saving surgery, which removes her ovaries and cervix. She had surgery to remove any cancer which meant she did not need radiotherapy or chemotherapy, and was no longer on her own.

But her journey does not end here.

“After I finished my treatment I wanted to make some changes,” Kath said.

“We don’t know what caused my cancer, but I have to admit that I carry a few extra pounds. So now I exercise and eat better to stay healthy. I also want to be learn for my family. “

Kath joins CRUK Race For Life each year, raising money and raising awareness about cancer.

“Reading a few words behind people about why they run back brings me back to all about the importance of this,” Kath said.

“My daughter’s statement is, ‘Diarrhea for our Mom who beat a stomach ache!’

“It simply came to our notice then cervical cancer rates are on the rise, and although weight is not the only risk factor, I want to encourage other women to live healthier for younger women to participate in what I do.

“I hope my story helps others make a difference in their lives.”


Investigate why obesity can lead to cancer


Learn more:
Identifying the mechanisms of genetic link between body mass index and risk of endometrial cancer: a Mendelian randomized study, BMC Medicine (2022). DOI: 10.1186 / s12916-022-02322-3, doi.org/10.1186/s12916-022-02322-3

hintWeight is almost double the risk of cervical cancer (2022, April 18) Retrieved 18 April 2022 from https://medicalxpress.com/news/2022-04-excess-weight-wemb-cancer.html

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