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Drug treatment for cataracts moves a step closer

Cataract in the human eye. Credit: Wikipedia.

A new revolutionary treatment of cataracts has shown excellent results in laboratory tests, giving hope that the condition, which is currently not only curable by surgery, will soon be cured him with drugs.

The results were published today in a peer-reviewed journal Ophthalmology and Ophthalmology Research.

Cataract is a cloud of eye contact that develops over time and affects visual acuity. It is caused by a lack of protein in the lens that causes inflammation of the protein, which transmits light and reduces diffusion to the eye. Cataracts result vision loss same to you blindness for millions of people around the world.

A team of international scientists, led by Professor Barbara Pierscionek, Assistant Dean (Research and Innovation) in the Faculty of Health, Education, Medicine and Social Care at Anglia Ruskin University (ARU), conducted a series of experiments. deep on a compound of oxysterol. which is recommended as a cataract treatment.

In laboratory experiments, treatment with oxysterol compound VP1-001 showed an improvement in the refractive profile — an important measure needed to maintain high concentration — in 61 % of lenses. This means that the protein structure of the lens is restored, resulting in the lens being more sensitive and sensitive. This was supported by a reduction in 46% of cases.

Professor Pierscionek, who is also a member of the Anglia Ruskin University Medical Center (ARU), said: it has never been tested. I see lenses. It is the first study of its kind in the world.

“It shows that there is a significant difference and improved visual acuity between the eyes with the same type of cataract used with the compounds compared to those without.

“Progress has been made in some types of cataract but not all, suggesting that this may be a specific treatment. cataracts. This suggests that differences between cataract types may be required when developing ophthalmic drugs. It is an important step forward in treating this common condition with medication instead of surgery. ”


New research could change cataract treatment


Learn more:
Oxysterol compounds in mouse ant- and αB-crystallin lenses 2 can improve the properties of the lens, Ophthalmology & Ophthalmology Research (2022).

hint: Anti-depressant for cataracts is moving step closer (2022, May 16) Retrieved 16 May 2022 from https://medicalxpress.com/news/2022-05-drug-treatment-cataracts-closer.html

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