The accident happened on Highway 180 and Dickenson Avenue at about 8:30 p.m.
The California Highway Patrol (CHP) says the victim was heading east on Highway 180 when he entered the opposite lane, right in the opposite lane, and collided with the truck.
The victim was seriously injured and died on the spot. The driver of the truck was not injured.
The CHP is trying to determine what led the victim to enter the opposite lane.
Police have not yet revealed the identities of the two drivers or whether alcohol or drugs were a factor in the accident.
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Driver killed in crash with truck in Fresno County Source link Driver killed in crash with truck in Fresno County