Since the BioNTech COVID-19 vaccine was introduced in October for children 5-11 years of age, many parents have been reluctant to be vaccinated. As of March 16, only 27% had received both vaccines, according to CDC data. A national survey published March 30’s New England Journal of Medicine now reports that vaccination for 5- to 11-year-olds reduces hospitalization with COVID-19 by more than two-thirds during omicron surgery and protection against serious illness.
The study, led by Adrienne Randolph, MD, MSc, at Boston Children’s Hospital and the Centers for Disease Control and Prevention, also found that the vaccine reduced COVID-19 exposure in young men aged 12-18 and was they are not well protected. severe illnessaccordingly review earlier this year.
“The reason a child gets COVID-19 is to prevent serious complications of SARS-CoV-2 infection, including hospitalization,” Randolph said. “This evidence suggests that the vaccine significantly reduces this risk in children 5 to 11 years of age. two differences. “
The study collected data from the ground Successful COVID-19 Networklaunched by Randolph in 2020. Includes 1,185 children with COVID-19 at 31 children’s hospitals across the United States: 918 young people aged 12 to 18 and 267 children aged 5 to 11
The exploration took place from July 2021 to February 17, 2022, during the delta and omicron climb. In children 5 to 11 years of age, immunization benefits can only be assessed during an omicron, because the vaccine is not approved until October 2021.
Research findings and conclusion
- Overall, 88% of patients hospitalized with COVID-19 were not vaccinated, and 25% had a serious illness that required life support intervention.
- Of children 5–11 years of age who were hospitalized with COVID-19, 92% had not been vaccinated. 16% of patients, however, need life-sustaining measures such as water intake. Of these, 90% were not vaccinated.
- Of those 12–18 years of age who were hospitalized with COVID-19, 87% had not been vaccinated. Twenty-seven percent suffer from chronic illness, and of these, 93% have not been vaccinated. Two children died.
Based on their observations, the researchers calculated that:
- Among children 5–11 years of age, two doses of Pfizer-BioNTech were 68% effective in preventing hospitalization during omicron. Because recently this age group has been eligible for immunizations, the numbers are not enough to evaluate illness differently.
- Among adolescents 12–18 years of age, vaccination was 92% effective on clinical with delta variants, falling to 40% with omicron variability. In terms of severe disease prevention, the vaccine was 96% effective in preventing severe illness during delta and 79% during omicron water.
Vaccination rates are lower and lower in children and adolescents
Pfizer / BioNTech prevention becomes available for children aged 16-18 in December 2020, for children aged 12-15 in May 2021, and for children aged 5-11 in October 2021. However, from March 16, 2002, only 57% of 12- to 17-year-olds and only 27% of 5- to 11-year-olds got two vaccinesaccording to Data collected by the CDC and the American Academy of Pediatrics.
“We hope our research will help parents decide whether to vaccinate their children and adolescents with COVID-19,” Randolph said. “The benefits are obviously more risky, because serious illnesses in children can lead to long-term consequences.”
Randolph and Manish Patel, MD, of the CDC were leading researchers on the study. Ashley Price, MPH, and Samantha Olson, MPH are the first authors on paper.
Samantha M. Olson et al, Effect of BNT162b2 immunity on Covid-19 Disease in Adolescents, New England Journal of Medicine (2022). DOI: 10.1056 / NEJMoa2117995
Boston Children’s Hospital
hintThe COVID vaccine for children aged 5-11 cut omicron hospitals by 68% (2022, March 30) and was recovered 30 March 2022 from https://medicalxpress.com/news/2022-03-covid-vaccination-children -agement-.html
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