COVID kidney injury may be twice as common as diagnosed

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A study led by the University of Queensland has found that millions of patients with COVID-19 are more likely to develop acute renal failure (AKI).

AKI is a condition in which the kidneys are unable to filter blood waste, which can lead to illness or even death.

Current data show nearly 20 percent of hospitalized patients with COVID-19 develop AKI, which is nearly 40 percent higher than those in intensive care.

Amma UQ Ph.D. candidate again kidney expert Dr. Marina Wainstein says the true number could double those numbers.

“Doctors are checking the amount of urine a patient has and the level of a space called creatinine in the bloodstream, which rises when the kidneys do not function properly, ”she said.

“However, if this creatinine increase occurs before a patient is admitted to the hospital, we may miss the AKI diagnosis and fail to manage the patient effectively during the initial, hospital days.”

Dr. Wainstein said that when researchers also measured a drop in creatinine levels, which usually follows premature ejaculation, the rate of AKI detection in COVID-19 patients doubled.

“This is a pretty scary research,” she said.

Dr. Wainstein says “losing” AKI in COVID-19 patients is risky.

“Although AKI has already begun to improve in the hospital, our study shows that these patients have a worse outcome in hospital and are more likely to die compared to patients who do not have AKI,” she said.

Dr. Wainstein says treatment for AKI can be as simple as checking a patient’s hydration level and stopping medications that could be toxic to the kidneys.

Superintendent of Drs. Sally Shrapnel, from UQ School of Mathematics and Physics, says collecting and analyzing work data during a disaster is a challenge.

“Majority data scientists Work with good registration details, but in this process it is collected by hospital staff operating under extreme conditions in different resource settings, ”she said.

“Cutting and refining data has become an integral part of the project.”

Dr. Shrapnel said the researchers were able to compile data from poorer countries, where AKI and the community also have more access.

“These people have limited access to health and can present at the end of the disease process.”

Dr. Shrapnel said the additional definition of AKI — which can identify emerging issues in the community — needs to be implemented as soon as possible.

“Now that we have the data showing a big gap in AKI diagnosis, it is time to test this definition in a clinical trial so that we can identify all AKI patients early and hopefully prevent these malignancies. reward.”

The study is published in The solution of PLOS.

Studies have revealed the risk factors for severe kidney injury after cerebral hemorrhage

Learn more:
Marina Wainstein et al, Using the extended KDIGO definition to diagnose severe kidney injury in patients with COVID-19: An international study using the ISARIC-WHO clinical behavior theory, The solution of PLOS (2022). DOI: 10.1371 / media.pmed.1003969

hintCOVID kidney damage can be as double as detected (2022, June 2) and recovered 2 June 2022 from html

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