COVID-19 hospital admission rare for children with arthritis

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Children and adolescents with rheumatic and musculoskeletal disorders (RMDs) are hospitalized without controversy with COVID-19, a study of more than 600 patients under the age of 19 found.

The study was published from 25 countries under the auspices of the University of Manchester and scientists from Boston Children’s Hospital Annals of the Rheumatic Diseases

Of the 607 patients, 378 had children idiopathic arthritis (JIA), 78 has auto-inflammatory inflammation, and 47 has system of lupus erythematosus or a mixture of meat diseases.

The majority of patients did not report any disease (83%), although 38 (6%) had eye swelling, a common condition in children with cold sores in developing children.

The study also found that those on biologic therapies, such as TNF inhibitors, did not appear to be at increased risk for developing COVID-19, compared to other children in the study who did not respond. medicine.

The data Physicians have been included in the group used in the European Association of Rheumatology (EULAR) COVID-19 Registry, Childhood Arthritis and Rheumatology Research Alliance (CARRA), and CARRA-sponsored COVID-19 Global Pediatric Rheumatology Database.

All COVID-19 cases occurred before the vaccine was administered internally youth in this study.

Dr Lianne Kearsley-Fleet, a pathologist at the University of Manchester, said: “Previous research has shown that most children and adolescents do not experience severe COVID-19, many are asymptomatic or have only mild symptoms. It is important to find out if this is true for those with RMDs, and the good news is that most of them appear to be healthy and suffer from mild COVID-19 infection. “

Min-Lee Chang, author of the paper that led the CARRA data analysis from Boston Children’s Hospital, said: “We certainly agree that preventive measures are important to follow to reduce the risk of getting SARS-CoV-2 infection.

“However these findings should help reassure parents and families that the potential for serious COVID-19 in many children and adolescents with JIA is relatively small.”

Although most children did well, 43 patients (7%) remained in the hospital.

Where hospitalizations occur, they are more common in those with severe RMDs such as lupus, vasculitis, or auto-inflammatory syndromes, rather than JIA. According to other studies, obese people are more than four times as likely to be hospitalized.

However, even among those hospitalized, most patients avoided severe illnesswith less than one in five needing oxygen or mechanical breathing support.

Professor Kimme Hyrich from the University of Manchester and a consultant on skin cancer, said: “The data are very reassuring but once again show the important link between obesity and the effects of severe COVID-19, with support. after the idea that the protective measures in these children should be strict. follow. “

Dr. Marc Natter, assistant professor of pediatrics at Harvard School of Medicine and a pediatrician leading the study for CARRA at Boston Children’s Hospital, said: “The general practice is for children, especially young children. ……………………………………………… COVID-19 is more common in adults with rheumatic fever, with reports of serious illness and death.

“But so far, little is known about the impact of infection and immunosuppression on the risk of severe COVID-19 in a large number of children with RMDs.

“This paper provides an important addition to the literature and should be reassuring to young people living with RMDs and their parents, although it emphasizes the need to understand there seems to be a general risk that needs to be addressed. COVID- 19 Vaccination, community outreach, and face masking where appropriate. ”

Registration data reveal the safety of COVID-19 in people with rheumatic and musculoskeletal disorders.

Learn more:
Lianne Kearsley-Fleet et al, The effects of SARS-CoV-2 infection on children and adolescents with previous rheumatic and musculoskeletal disorders, Annals of the Rheumatic Diseases (2022). DOI: 10.1136 / annrheumdis-2022-222241

hintCOVID-19 is rarely admitted to the hospital for children with arthritis (2022, March 30) and recovered 30 March 2022 from -children.html

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