The largest ever study of the Arab genome reveals the oldest of the modern Middle Eastern population, and that modern humans may have first spread around the world.
Today, the Arabian Peninsula, which includes Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab Emirates, has long served as an important crossroads between Africa, Europe and Asia.recently Archeology, With fossils DNA Findings suggest that analyzing the Middle East and its people can reveal more about how modern people first behaved. Escaped from africa And for the rest of the world.
So far, little research has been done on Arab genetics. In a new study, researchers performed the first large-scale analysis of the genetics of the population of the Middle East, examining DNA from 6,218 adults randomly selected from the Qatar Health Database, which is now available elsewhere in the world. Compared with the DNA of people living in the area. DNA from ancient humans who once lived in Africa, Europe and Asia.
“This is the first major study of the Arab population,” Younes Mokrab, co-author of the research co-author, who is responsible for the medical and collective genomics lab at Sidra Medicine in Doha, Qatar, told Live Science.
Scientists have discovered that DNA from groups in the Middle East has made important genetic contributions to communities in Europe, South Asia, and even South America. Those groups, they said.
“Arab ancestors are an important ancestral component of many modern populations,” Moclub said. “This means that what is discovered in this area has a direct impact on the population of other areas.”
New findings also suggest that the ancestors of the Arabian Peninsula group split from early Africans about 90,000 years ago. This is about the same time that European and South Asian ancestors split from early Africans, supporting the idea that people migrated from Africa to other parts of the world via Arabia. The researchers said.
“Arabia is the basis of early migration from Africa,” Moclub said.
Later, the Arabian Peninsula group clearly split from its ancestral Europeans about 42,000 years ago and from the South Asian population about 32,000 years ago. “Previously, the Arab population was thought to come from a wide range of European populations,” Moclub said.
After modern humans left Africa, they encountered other now extinct human pedigrees-and sometimes mated- Neanderthals And the Denisovans whose ancestors left Africa long before modern people left, and were virtually exclusively discovered in Europe and Asia. “The timeline found in our study when Arabs diverged from other populations is why Neanderthal DNA is much rarer in the Arab population than in the later mixed population with the ancient Hominini. Explains, “Moclub said.
Moreover, after comparing the modern human genome with ancient human DNA, scientists discovered that a unique group of Arabs on the peninsula may be the oldest of all modern Middle Eastern populations, Said Moclub. Members of this group may be the closest relatives of the earliest known peasants and hunter-gatherers to occupy the ancient Middle East, the researchers said.
Scientists said the ancestral Arab group appeared to have experienced multiple divisions 12,000 to 20,000 years ago. This is consistent with Arabia’s arid way, with some groups moving to more fertile areas to create a community of settlers and others living in arid areas that further promote the nomadic lifestyle. I’m continuing.
A new study found a high rate of inbreeding in several groups on the Arab Peninsula dating back to ancient times. This is probably because the tribal nature of these cultures raises barriers to marriage outside the tribal group. These new discoveries reveal the causes of specific hereditary diseases and the communities shown in the study, as incest may highlight rare mutations that can increase the risk of the disease. Researchers said it could lead to precision medicine that would help diagnose and treat the disease.
Scientists elaborated on the findings online in the journal on October 12th Nature Communications..
Originally published in Live Science.
Arabia was ‘cornerstone’ in early human migrations out of Africa, study suggests Source link Arabia was ‘cornerstone’ in early human migrations out of Africa, study suggests