Vaccines given to women before they give birth have no effect on the risk of childhood conditions, such as asthma or eczema, according to a study by researchers at the Universities of Birmingham and Warwick.
The study, published today in BMJ, provides additional evidence to support the recommendations of the National Institute of Health and Care (NICE). These suggest that mothers should be given antibiotics before undergoing surgery. The guide, updated in 2011, is designed to reduce the risk of infection, and says the mother will benefit most from the antibiotics given shortly before the cesarean section, rather than after the umbilical cord is compressed. .
Cesarean delivery is common, with one-third of babies born in the UK this way, but women are more likely to have an infection, which is why antibiotics are given. There are no known health effects for infants from these antibiotics.
If antibiotics are given before the umbilical cord is compressed, however, it will pass parents and can affect microbes in the gut. These microbes include bacteria that are thought to be beneficial to the health and development of the immune system.
Previous research has found a link between the presence of bacteria and other organisms in the gut — the microbiome — and the development of allergic conditions such as them. eczema same to you asthma. Finding out that these terms are unrelated to the mother being given antibiotics for cesarean delivery so it is an important area of play.
A team of researchers from the Universities of Birmingham and Warwick compared the risk of comorbidities in the first five years after birth in infants born by cesarean section both before and after the change in NICE guidelines. They used the data of millions of children born between 2006 and 2018, which is included in the UK health records.
Their findings suggest that immunization before the cesarean section has no effect on the risk of these developing conditions.
Senior author Dr. Dana Sumilo, a resident of the University of Warwick, said, “Cervical cancer, such as traumatic brain injury, can be dangerous during childbirth immediately after birth. Antibiotics do not work for newborns and our research shows that it does not affect the risk of diseases such as asthma and eczema in children. “
Professor Andrew Shennan, Clinical Director, NIHR Clinical Research Network South London, said, “These new developments provide further evidence that immunization improves health outcomes for mothers and their infants before. cesarean section.
“This arms doctors with vital evidence that allows them to prove it vaccine they are used wisely and in the best place for the most effective treatment. ”
Long-term effects of pre-eclampsia and post-operative immunosuppression on infants born by caesarean section: a long-term study of British electronic health data, BMJ (2022).
University of Birmingham
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