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Antibiotic-free hydrogen peroxide e-bandages treat wound infections

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According to a new study by researchers at the Mayo Clinic and Washington State University, e-bandages may be an alternative to antibiotics for the treatment of chronic diseases. The study was presented at ASM Microbe 2022, the annual meeting of the American Society for Microbiology.

In a recent study conducted in mice, novel hydrogen peroxide providing bandages and electronics /Chemical Properties (chemical bandages or e-bandage), under the power of portable electrical devices, reduces the resistance of methicillin. Staphylococcus aureus (MRSA) biofilm-deficient cells by 99% after 2 days of treatment.

In people suffering from traumatic injuries, routine care involves cleaning the wound using a variety of solutions — including hydrogen peroxide, applying antiseptic cream or ointment, and in some cases, administering. . vaccine. If the wounds do not heal, they can progress to a stage of severe injury that can be difficult to control. Research has shown that common lesions carry different types of living organisms (communities of microorganisms that coexist with each other). Cells in such films of biofils can thrive and resist the effects of antibiotics, which is why they are difficult to treat even with long-term antibiotics. Long-term use of antibiotics may result in the selection of resistant strains of the virus. The presence of biofilms in wounds also delays wound healing; Injuries associated with biofilm are common in patients who are older, have diabetes or are unvaccinated.

“Injuries are numerous and can be challenging to treat. Therefore, it is important to develop new strategies, technologies and management strategies that are not dependent on antibiotics,” said study author Yash S. Raval, Ph.D. .D., General Research. Fellow, Department of Clinical Biology at Mayo Clinic in Rochester, Minn.

Hydrogen peroxide is used to clean wounds. Although hydrogen peroxide has antibacterial and antifungal properties, hydrogen peroxide is not scientifically stable and therefore, its effects are short-lived. Dr. Raval and colleagues have developed an e-bandage to continue to produce hydrogen peroxide as a treatment for wounds

“Specifically, we have developed and tested the antimicrobial properties of a new type of bandage that continues to produce hydrogen peroxide through specific energy-saving applications,” said Dr. Raval.

In the study, the researchers induced lesions on rats and infected them with MRSA to establish lesions of MRSA biofilms. They then treat the infected wounds through a flexible e-bandage. The hydrogen peroxide-The production of e-bandage reduces the number of virus cells by 99 percent.


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