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About 3 grams a day of omega-3 fatty acids may lower blood pressure, more research needed

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About 3 grams per day of omega-3 fatty acids, consumed in food or supplements, has become the best daily remedy to help lower blood pressure, according to a study published today in Journal of the American Heart Associationopen access, reviewed by the American Heart Association.

Omega-3 fatty acid docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) is found in fatty fish, such as salmon, tuna, sardines, trout, herring and oysters. Some people also take DHA and EPA in combination in supplements. While some studies suggest that use omega-3 fatty acid can reduce blood pressure, the optimal amount needed to lower blood pressure is not clear. Public Health Centers have established an adequate diet of omega-3 fatty acids for healthy people at 1.1- 1.6 grams per day, depending on age and sex.

“According to our study, middle-aged adults may experience a significant reduction in blood pressure from consuming about 3 grams per day of these fatty acids,” said study author Xinzhi Li, MD, Ph.D., assistant professor and director of programs at the School. He studied Pharmacy at Macau University of Science and Technology in Macau, China.

The researchers examined the results of 71 clinical trials from around the world published from 1987 to 2020. The study examined the relationship between high blood pressure and omega-3 fatty acids DHA and EPA (either individually or combination) in people 18 years of age with or without high blood pressure or cholesterol deficiency. There were approximately 5,000 participants, ranging in age from 22 to 86. Participants took a dietary supplement and / or fatty acid-based medication for an average of 10 weeks.

The study found:

  • Compared to adults who did not consume EPA and DHA, those who consumed between 2 to 3 grams per day of combined DHA and EPA omega-3 fatty acids (in supplement, diet or both) reduced systolic (above figure ) and diastolic (country code). ) high blood pressure and average 2 mm Hg.
  • Consuming more than 3 grams of omega-3 fatty acids daily may increase the benefits of lowering blood pressure for adults with high blood pressure or blood lipids:
  • 3 g and omega-3 a day. systolic hypertension (SBP) decreased by an average of 4.5 mm Hg for those with hypertension, and about 2 mm Hg on average for those without.
  • At 5g a day of omega-3s, SBP is about 4 mm Hg for those with high blood pressure and less than 1 mm Hg on average for those without it.
  • Similar differences were observed in people with high blood pressure and in those over 45 years of age.

About 4-5 ounces of Atlantic salmon provides 3 grams of omega 3 fatty acids. Regular fish oil contains about 300 mg of omega-3s per pill, but the doses vary widely.

“Many studies have reported on fatty acids instead of on EPA and omega-3 fatty acids in the diet, suggesting supplements may be an alternative for those who cannot eat fatty fish regularly, said Li. “Algae products with EPA and DHA fatty acid are also an option for people who do not eat fish or others. animal products. “

The US Food and Drug Administration (FDA) announced in June 2019 that he did not reject some health claims that consumed EPA and DHA omega-3 fatty acids in food or dietary supplements may reduce the risk of hypertension as well coronary heart disease. However, they noted that the evidence was inaccurate and inaccurate.

“Our research supports FDA guidelines that EPA and DHA omega-3 fatty acids can reduce the risk of heart disease by lowering blood pressure, especially among people who have already been diagnosed with high blood pressure,” he said. “However, while our findings may add strong corroborative evidence, it does not open the door to claim authorized omega-3 fatty acids. fatty acid in accordance with FDA guidelines. “

The scope of the review includes differences in how high blood pressure was measured, and whether the study examined omega-3 intake from supplements or foods, which may affect final strength.

The Recommended by the American Heart Association eating two servings (3-4 oz cooked) of fish per week (especially fatty fish such as salmon) as part of a healthy heart diet.

The co-authors are Xin Zhang, Ph.D .; Jennifer A. Ritonja, Ph.D .; Na Zhou, Ph.D .; and Bingshu E. Chen, Ph.D. Author information is listed in the text.


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Learn more:
Omega-3 Polyunsaturated Fatty Acids and Blood Pressure: Answers-Meta-Research of Distribution Control Experiments, Journal of the American Heart Association (2022). DOI: 10.1161 / JAHA.121.025071

hint: About 3 grams a day of omega-3 fatty acids can lower blood pressure, more research is needed (2022, June 1) Retrieved 1 June 2022 from https://medicalxpress.com/news/2022-06-grams -day-omega -fatsi-acid.html

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